Carcinolipin | CAS# 19477-24-8

MedKoo Cat#: 412332 | Name: Carcinolipin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Carcinolipin is a biochemical with endogenous carcinogenic effects

Chemical Structure

Carcinolipin

CAS#19477-24-8

Theoretical Analysis

MedKoo Cat#: 412332

Name: Carcinolipin

CAS#: 19477-24-8

Chemical Formula: C44H78O2

Exact Mass: 638.6002

Molecular Weight: 639.11

Elemental Analysis: C, 82.69; H, 12.30; O, 5.01

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Carcinolipin; BRN2493354; BRN-2493354; BRN 2493354

IUPAC/Chemical Name

Cholest-5-en-3-beta-ol, 14-methylhexadecanoate

InChi Key

ILZPADCYIWUDSX-JZMMRQARSA-N

InChi Code

InChI=1S/C44H78O2/c1-8-34(4)21-17-15-13-11-9-10-12-14-16-18-23-42(45)46-37-28-30-43(6)36(32-37)24-25-38-40-27-26-39(35(5)22-19-20-33(2)3)44(40,7)31-29-41(38)43/h24,33-35,37-41H,8-23,25-32H2,1-7H3/t34?,35-,37+,38+,39-,40+,41+,43+,44-/m1/s1

SMILES Code

CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(CCCCCCCCCCCCC(C)CC)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 639.11 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Hradec J, Dolejs L. The chemical constitution of carcinolipin. Biochem J. 1968 Mar;107(2):129-34. doi: 10.1042/bj1070129. PMID: 5689245; PMCID: PMC1198637. 2: Hradec J. Effect of carcinolipin on the adenosine triphosphatase activity of isolated cellular fractions. Nature. 1965 Aug 28;207(5000):982-3. doi: 10.1038/207982b0. PMID: 4223269. 3: Hradec J. A chromatographic method for the quantitative determination of cholesterol 14-methylhexadecanoate (carcinolipin) in biological materials. J Chromatogr. 1968 Feb 6;32(3):511-8. doi: 10.1016/s0021-9673(01)80523-9. PMID: 4295862. 4: FRIBORSKY V. LIVER CHANGES CAUSED BY CARCINOLIPIN. Neoplasma. 1964;11:55-61. PMID: 14116775. 5: Hradec J, Mensík P. Purification of the fatty acid present in carcinolipin. J Chromatogr. 1968 Feb 6;32(3):502-10. doi: 10.1016/s0021-9673(01)80522-7. PMID: 5689452. 6: HRADEC J, KRUML J. Carcinolipin: an endogenous carcinogenic substance. Nature. 1960 Jan 2;185:55. doi: 10.1038/185055a0. PMID: 14403538. 7: Kolesnichenko TS, Savluchinskaia LA. O transplatsentarnom deĭstvii kartsinolipina [Transplacental action of carcinolipin]. Vopr Onkol. 1975;21(3):101-3. Russian. PMID: 1130012. 8: HRADEC J. CARCINOLIPIN--AN ESSENTIAL FACTOR IN PROTEIN SYNTHESIS. Acta Unio Int Contra Cancrum. 1964;20:926-8. PMID: 14274754. 9: Shabad LM, Kolesnichenko TS, Savluchinskaya LA. Transplacental effect of carcinolipin in mice. Neoplasma. 1973;20(3):347-8. PMID: 4725520. 10: HRADEC J. Effect of carcinolipin on protein synthesis in cell-free systems. Biochim Biophys Acta. 1961 Feb 12;47:149-57. doi: 10.1016/0006-3002(61)90840-x. PMID: 13716315.