NAA-004 | CAS# 402934-69-4 | Biochemical

MedKoo Cat#: 574952 | Name: NAA-004

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NAA-004, also known as APAZA, has been shown to significantly inhibit toxin A-induced myeloperoxidase activity, luminal fluid accumulation, and structural damage to the colon in instances of toxin A-induced colitis.

Chemical Structure

NAA-004

CAS#402934-69-4

Theoretical Analysis

MedKoo Cat#: 574952

Name: NAA-004

CAS#: 402934-69-4

Chemical Formula: C15H12N2O5

Exact Mass: 300.0746

Molecular Weight: 300.27

Elemental Analysis: C, 60.00; H, 4.03; N, 9.33; O, 26.64

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

APAZA, NAA-004, Nobex-AA-004, INN-108

IUPAC/Chemical Name

5-((E)-(4-(Carboxymethyl)phenyl)azo)-2-hydroxy-benzoic acid

InChi Key

FNRNBCNUWGWVFO-WUKNDPDISA-N

InChi Code

InChI=1S/C15H12N2O5/c18-13-6-5-11(8-12(13)15(21)22)17-16-10-3-1-9(2-4-10)7-14(19)20/h1-6,8,18H,7H2,(H,19,20)(H,21,22)/b17-16+

SMILES Code

O=C(O)C1=CC(/N=N/C2=CC=C(CC(O)=O)C=C2)=CC=C1O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 300.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. McVey DC, Liddle RA, Riggs-Sauthier J, Ekwuribe N, Vigna SR. Inhibition of Clostridium difficile toxin A-induced colitis in rats by APAZA. Dig Dis Sci. 2005 Mar;50(3):565-73. doi: 10.1007/s10620-005-2476-1. PMID: 15810644.