Dimethomorph | CAS#110488-70-5 | Systemic fungicide

MedKoo Cat#: 463277 | Name: Dimethomorph

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dimethomorph is a fungicide with systemic function. It is used for treating mildew and root rot caused by organisms such as Pythium and Phytophthora species.

Chemical Structure

Dimethomorph

CAS#110488-70-5

Theoretical Analysis

MedKoo Cat#: 463277

Name: Dimethomorph

CAS#: 110488-70-5

Chemical Formula: C21H22ClNO4

Exact Mass: 387.1237

Molecular Weight: 387.86

Elemental Analysis: C, 65.03; H, 5.72; Cl, 9.14; N, 3.61; O, 16.50

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

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Synonym

Dimethomorph; Dimethomorph, (E)-; E-Dimethomorph; E Dimethomorph; Dimethomorph E; Dimethomorph-E;

IUPAC/Chemical Name

(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholinoprop-2-en-1-one

InChi Key

QNBTYORWCCMPQP-NBVRZTHBSA-N

InChi Code

InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+

SMILES Code

COc1c(OC)cc(/C(c2ccc(Cl)cc2)=C/C(N3CCOCC3)=O)cc1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 387.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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AhR-activating pesticides increase the bovine ABCG2 efflux activity in MDCKII-bABCG2 cells. PLoS One. 2020 Aug 7;15(8):e0237163. doi: 10.1371/journal.pone.0237163. PMID: 32764792; PMCID: PMC7413513. 5: Pérez-Mayán L, Ramil M, Cela R, Rodríguez I. Multiresidue procedure to assess the occurrence and dissipation of fungicides and insecticides in vineyard soils from Northwest Spain. Chemosphere. 2020 Dec;261:127696. doi: 10.1016/j.chemosphere.2020.127696. Epub 2020 Jul 18. PMID: 32711239. 6: Zambito Marsala R, Capri E, Russo E, Bisagni M, Colla R, Lucini L, Gallo A, Suciu NA. First evaluation of pesticides occurrence in groundwater of Tidone Valley, an area with intensive viticulture. Sci Total Environ. 2020 Sep 20;736:139730. doi: 10.1016/j.scitotenv.2020.139730. Epub 2020 May 26. PMID: 32504868. 7: Zhang C, Li J, Wu X, Long Y, An H, Pan X, Li M, Dong F, Zheng Y. Rapid degradation of dimethomorph in polluted water and soil by Bacillus cereus WL08 immobilized on bamboo charcoal-sodium alginate. J Hazard Mater. 2020 Nov 5;398:122806. doi: 10.1016/j.jhazmat.2020.122806. Epub 2020 May 16. PMID: 32497856. 8: Acosta-Sánchez A, Soto-Garita C, Masís-Mora M, Cambronero-Heinrichs JC, Rodríguez-Rodríguez CE. Impaired pesticide removal and detoxification by biomixtures during the simulated pesticide application cycle of a tropical agricultural system. Ecotoxicol Environ Saf. 2020 Jun 1;195:110460. doi: 10.1016/j.ecoenv.2020.110460. Epub 2020 Mar 19. PMID: 32199216. 9: Fu Y, Dou X, Lu Q, Qin J, Luo J, Yang M. Comprehensive assessment for the residual characteristics and degradation kinetics of pesticides in Panax notoginseng and planting soil. Sci Total Environ. 2020 Apr 20;714:136718. doi: 10.1016/j.scitotenv.2020.136718. Epub 2020 Jan 15. PMID: 31982747. 10: Celeiro M, Vazquez L, Nurerk P, Kabir A, Furton KG, Dagnac T, Llompart M. Fabric phase sorptive extraction for the determination of 17 multiclass fungicides in environmental water by gas chromatography-tandem mass spectrometry. J Sep Sci. 2020 May;43(9-10):1817-1829. doi: 10.1002/jssc.201901232. Epub 2020 Feb 5. PMID: 31958358. 11: Yang M, Luo F, Zhang X, Zhou L, Lou Z, Zhao M, Chen Z. Dissipation and Risk Assessment of Multiresidual Fungicides in Grapes under Field Conditions. J Agric Food Chem. 2020 Jan 29;68(4):1071-1078. doi: 10.1021/acs.jafc.9b06064. Epub 2019 Dec 27. PMID: 31841622. 12: Ma M, Chen C, Yang G, Wang Y, Wang T, Li Y, Qian Y. Combined anti-androgenic effects of mixtures of agricultural pesticides using in vitro and in silico methods. Ecotoxicol Environ Saf. 2019 Dec 30;186:109652. doi: 10.1016/j.ecoenv.2019.109652. Epub 2019 Oct 9. PMID: 31605955. 13: Chen L, Zhao B, Fan Z, Hu M, Li Q, Hu W, Li J, Zhang J. Discovery of Novel Isothiazole, 1,2,3-Thiadiazole, and Thiazole-Based Cinnamamides as Fungicidal Candidates. 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RNA- seq analysis of the response of plant-pathogenic oomycete Phytophthora parasitica to the fungicide dimethomorph. Rev Argent Microbiol. 2019 Jul- Sep;51(3):268-277. doi: 10.1016/j.ram.2018.08.007. Epub 2019 Jan 19. PMID: 30670299. 18: Wang S, Zhang Q, Yu Y, Chen Y, Zeng S, Lu P, Hu D. Residues, dissipation kinetics, and dietary intake risk assessment of two fungicides in grape and soil. Regul Toxicol Pharmacol. 2018 Dec;100:72-79. doi: 10.1016/j.yrtph.2018.10.015. Epub 2018 Oct 22. PMID: 30359702. 19: Vargas TS, Salustriano NA, Klein B, Romão W, Silva SRCD, Wagner R, Scherer R. Fungicides in red wines produced in South America. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Nov;35(11):2135-2144. doi: 10.1080/19440049.2018.1529439. Epub 2018 Oct 23. PMID: 30352006. 20: European Food Safety Authority (EFSA), Brancato A, Brocca D, Carrasco Cabrera L, De Lentdecker C, Erdos Z, Ferreira L, Greco L, Jarrah S, Kardassi D, Leuschner R, Lostia A, Lythgo C, Medina P, Miron I, Molnar T, Pedersen R, Reich H, Sacchi A, Santos M, Stanek A, Sturma J, Tarazona J, Theobald A, Vagenende B, Villamar-Bouza L. Evaluation of confirmatory data following the Article 12 MRL review for dimethomorph. EFSA J. 2018 Oct 19;16(10):e05433. doi: 10.2903/j.efsa.2018.5433. PMID: 32625714; PMCID: PMC7009380.