STING agonist 1a is an agonist of stimulator of interferon genes (STING). It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay. STING agonist 1a induces expression of IFN-β, IL-6, and chemokine ligand 10 in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151.
MedKoo Cat#: 463224
Name: STING Agonist 1a
CAS#: 652142-94-4
Chemical Formula: C19H11Cl2N5O
Exact Mass: 395.0341
Molecular Weight: 396.23
Elemental Analysis: C, 57.59; H, 2.80; Cl, 17.89; N, 17.68; O, 4.04
The following data is based on the product molecular weight 396.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
