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MedKoo Cat#: 463211 | Name: E 3040

Description:

WARNING: This product is for research use only, not for human or veterinary use.

E 3040 is a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase. It is involved with eicosanoid production. E 3040 also has anti-inflammatory properties.

Chemical Structure

E 3040
E 3040
CAS#145096-30-6

Theoretical Analysis

MedKoo Cat#: 463211

Name: E 3040

CAS#: 145096-30-6

Chemical Formula: C16H17N3OS

Exact Mass: 299.1092

Molecular Weight: 299.39

Elemental Analysis: C, 64.19; H, 5.72; N, 14.04; O, 5.34; S, 10.71

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
E 3040; E3040; E-3040;
IUPAC/Chemical Name
5,7-dimethyl-2-(methylamino)-4-(pyridin-3-ylmethyl)benzo[d]thiazol-6-ol
InChi Key
IONAQTGMWFXHIX-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H17N3OS/c1-9-12(7-11-5-4-6-18-8-11)13-15(10(2)14(9)20)21-16(17-3)19-13/h4-6,8,20H,7H2,1-3H3,(H,17,19)
SMILES Code
CNc(n1)sc2c1c(Cc3cnccc3)c(C)c(O)c2C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 299.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Oketani K, Nagakura N, Harada K, Inoue T. In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production. Eur J Pharmacol. 2001 Jun 22;422(1-3):209-16. doi: 10.1016/s0014-2999(01)01022-6. PMID: 11430933. 2: Yamada H, Kotaki H, Furitsu H, Sawada Y, Iga T. Mechanism of the uricosuric action of the anti-inflammatory drug E3040 used to treat inflammatory bowel disease I: study using a rat model of hyperuricemia. Biopharm Drug Dispos. 1999 Mar;20(2):77-83. doi: 10.1002/(sici)1099-081x(199903)20:2<77::aid- bdd154>3.0.co;2-d. PMID: 10206322.