MedKoo Cat#: 412211 | Name: Oleyl alcohol
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Oleyl alcohol is an emulsifying agent.

Chemical Structure

Oleyl alcohol
Oleyl alcohol
CAS#143-28-2

Theoretical Analysis

MedKoo Cat#: 412211

Name: Oleyl alcohol

CAS#: 143-28-2

Chemical Formula: C18H36O

Exact Mass: 268.2766

Molecular Weight: 268.49

Elemental Analysis: C, 80.53; H, 13.52; O, 5.96

Price and Availability

Size Price Availability Quantity
100g USD 211.90 2 Weeks
1000g USD 347.80 2 Weeks
2500g USD 576.00 2 Weeks
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Related CAS #
No Data
Synonym
Oleyl alcohol; Adol320; Adol-320; Adol 320
IUPAC/Chemical Name
(Z)-octadec-9-en-1-ol
InChi Key
InChi Code
SMILES Code
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Oleyl alcohol is an emulsifying agent.
In vitro activity:
The hexanol extraction efficiency and inhibitory effects on C. carboxidivorans P7 of 2-butyl-1-octanol, hexyl hexanoate and oleyl alcohol were examined, and oleyl alcohol was selected as the extraction solvent. Oleyl alcohol was added at the beginning of fermentation and during fermentation or a small volume of oleyl alcohol was repeatedly added during fermentation. The addition of a small volume of oleyl alcohol during fermentation was the most effective for CO consumption and hexanol production (5.06 g/L), yielding the highest known hexanol titer through any type of fermentation including gas fermentation. Hexanol production was further enhanced to 8.45 g/L with the repeated addition of oleyl alcohol and ethanol during gas fermentation. Reference: Bioresour Technol. 2023 Jan;367:128201. https://pubmed.ncbi.nlm.nih.gov/36374655/
In vivo activity:
This study administered [14C]oleic acid and oleyl alcohol as lipid emulsion intraduodenally in unanesthetized lymph-cannulated rats and measured the lymphatic output of oleic acid. Furthermore, rats were fed oleyl alcohol as a dietary component for 20 days, and fecal lipid and the weight of adipose tissues were measured. In lymph-cannulated rats, triglyceride and [14C]oleic acid output in the lymph were significantly lower in the presence of oleyl alcohol when compared with the absence of oleyl alcohol in a dose-dependent manner. Reference: J Nutr Sci Vitaminol (Tokyo). 2000 Dec;46(6):302-8. https://pubmed.ncbi.nlm.nih.gov/11227802/

Preparing Stock Solutions

The following data is based on the product molecular weight 268.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
1. Oh HJ, Gong G, Ahn JH, Ko JK, Lee SM, Um Y. Effective hexanol production from carbon monoxide using extractive fermentation with Clostridium carboxidivorans P7. Bioresour Technol. 2023 Jan;367:128201. doi: 10.1016/j.biortech.2022.128201. Epub 2022 Oct 28. PMID: 36374655. 2. Jameel BM, Huynh A, Chadha A, Pandey S, Duncan J, Chandler M, Baki G. Computer-based formulation design and optimization using Hansen solubility parameters to enhance the delivery of ibuprofen through the skin. Int J Pharm. 2019 Oct 5;569:118549. doi: 10.1016/j.ijpharm.2019.118549. Epub 2019 Aug 5. PMID: 31394188. 3. Murota K, Kawada T, Matsui N, Sakakibara M, Takahashi N, Fushiki T. Oleyl alcohol inhibits intestinal long-chain fatty acid absorption in rats. J Nutr Sci Vitaminol (Tokyo). 2000 Dec;46(6):302-8. doi: 10.3177/jnsv.46.302. PMID: 11227802.
In vitro protocol:
1. Oh HJ, Gong G, Ahn JH, Ko JK, Lee SM, Um Y. Effective hexanol production from carbon monoxide using extractive fermentation with Clostridium carboxidivorans P7. Bioresour Technol. 2023 Jan;367:128201. doi: 10.1016/j.biortech.2022.128201. Epub 2022 Oct 28. PMID: 36374655. 2. Jameel BM, Huynh A, Chadha A, Pandey S, Duncan J, Chandler M, Baki G. Computer-based formulation design and optimization using Hansen solubility parameters to enhance the delivery of ibuprofen through the skin. Int J Pharm. 2019 Oct 5;569:118549. doi: 10.1016/j.ijpharm.2019.118549. Epub 2019 Aug 5. PMID: 31394188.
In vivo protocol:
1. Murota K, Kawada T, Matsui N, Sakakibara M, Takahashi N, Fushiki T. Oleyl alcohol inhibits intestinal long-chain fatty acid absorption in rats. J Nutr Sci Vitaminol (Tokyo). 2000 Dec;46(6):302-8. doi: 10.3177/jnsv.46.302. PMID: 11227802.
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