CRBN PROTAC® 14a is a cereblon degrader. It comprises a ligand for Von Hippel Lindau (VHL) protein joined by a linker to a cereblon targeting ligand. It preferentially degrades cereblon, and induces rapid and profound cereblon degradation.
MedKoo Cat#: 463179
Name: CRBN PROTAC® 14a
CAS#: 2358775-70-7
Chemical Formula: C53H72N8O13S
Exact Mass: 1060.4940
Molecular Weight: 1061.26
Elemental Analysis: C, 59.98; H, 6.84; N, 10.56; O, 19.60; S, 3.02
The following data is based on the product molecular weight 1,061.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
