MedKoo Cat#: 574899 | Name: TCS PIM-1 1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TCS PIM-1 1 is an ATP-competitive Pim-1 kinase inhibitor.

Chemical Structure

TCS PIM-1 1
TCS PIM-1 1
CAS#491871-58-0

Theoretical Analysis

MedKoo Cat#: 574899

Name: TCS PIM-1 1

CAS#: 491871-58-0

Chemical Formula: C18H11BrN2O2

Exact Mass: 366.0004

Molecular Weight: 367.20

Elemental Analysis: C, 58.88; H, 3.02; Br, 21.76; N, 7.63; O, 8.71

Price and Availability

Size Price Availability Quantity
100mg USD 1,250.00 2 Weeks
200mg USD 1,950.00 2 Weeks
500mg USD 3,250.00 2 Weeks
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Related CAS #
No Data
Synonym
TCS PIM-1 1; SC204330; SC-204330; SC 204330
IUPAC/Chemical Name
3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone
InChi Key
SVSYJTYGPLVUOZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H11BrN2O2/c19-12-6-7-17(22)14(8-12)16-9-13(11-4-2-1-3-5-11)15(10-20)18(23)21-16/h1-9,22H,(H,21,23)
SMILES Code
O=C1C(C#N)=C(C2=CC=CC=C2)C=C(C3=C(O)C=CC(Br)=C3)N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 367.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1.Cheney et al (2007) Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase. Bioorg.Med.Chem.Letts. 17 1679 PMID: 17251021