MedKoo Cat#: 574897 | Name: TC-G 24
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TC-G 24 is a brain penetrant GSK-3β inhibitor that has been shown to increase liver glycogen reserves in rodents.

Chemical Structure

TC-G 24
TC-G 24
CAS# 1257256-44-2

Theoretical Analysis

MedKoo Cat#: 574897

Name: TC-G 24

CAS#: 1257256-44-2

Chemical Formula: C15H11ClN4O3

Exact Mass: 330.0520

Molecular Weight: 330.73

Elemental Analysis: C, 54.48; H, 3.35; Cl, 10.72; N, 16.94; O, 14.51

Price and Availability

Size Price Availability Quantity
10mg USD 395.00 2 Weeks
50mg USD 1,280.00 2 Weeks
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Related CAS #
No Data
Synonym
TC-G 24
IUPAC/Chemical Name
N-(3-Chloro-4-methylphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazol-2-amine
InChi Key
JYCNWQGNEJYDQS-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H11ClN4O3/c1-9-2-5-11(8-13(9)16)17-15-19-18-14(23-15)10-3-6-12(7-4-10)20(21)22/h2-8H,1H3,(H,17,19)
SMILES Code
O=[N+](C1=CC=C(C2=NN=C(NC3=CC=C(C)C(Cl)=C3)O2)C=C1)[O-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 330.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Khanfar et al (2010) Discovery of novel GSK-3β inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand- and structure-based virtual screening. J.Med.Chem. 53 8534 PMID: 21082766