MedKoo Cat#: 463113 | Name: NSC 707
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide, also known as NSC 707, is an antimicrobial agent. It is active against the Gram-negative bacteria E. coli, P. aeruginosa, and S. marcescens, the Gram-positive bacteria S. aureus, M. luteus, and B. cereus, and the fungi C. albicans, G. candidum, T. rubrum, F. oxysporum, A. flavus, and S. brevicaulis. 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is also a precursor in the synthesis of other antimicrobial agents, as well as compounds with anticancer activity.

Chemical Structure

NSC 707
NSC 707
CAS#5351-71-3

Theoretical Analysis

MedKoo Cat#: 463113

Name: NSC 707

CAS#: 5351-71-3

Chemical Formula: C7H9N3S2

Exact Mass: 199.0238

Molecular Weight: 199.29

Elemental Analysis: C, 42.19; H, 4.55; N, 21.09; S, 32.17

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 550.00 2 Weeks
25mg USD 950.00 2 Weeks
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Related CAS #
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Synonym
NSC 707; NSC 707; NSC 707; 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide; 1-(Thiophen-2-yl)ethanone thiosemicarbazone;
IUPAC/Chemical Name
(E)-2-(1-(thiophen-2-yl)ethylidene)hydrazine-1-carbothioamide
InChi Key
PJVHAJJEMJNPHN-WEVVVXLNSA-N
InChi Code
InChI=1S/C7H9N3S2/c1-5(9-10-7(8)11)6-3-2-4-12-6/h2-4H,1H3,(H3,8,10,11)/b9-5+
SMILES Code
S=C(N)N/N=C(C1=CC=CS1)\C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide, also known as NSC 707, is an antimicrobial agent.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 199.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Thanigaimalai P, Lee KC, Sharma VK, Roh E, Kim Y, Jung SH. Ketonethiosemicarbazones: structure-activity relationships for their melanogenesis inhibition. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3527-30. doi: 10.1016/j.bmcl.2011.04.146. Epub 2011 May 5. PMID: 21601449.