MedKoo Cat#: 574870 | Name: SAR-216471 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SAR-216471 hydrochloride is a P2Y12 antagonist with anti-platelet and anti-thrombotic activity.

Chemical Structure

SAR-216471 HCl
SAR-216471 HCl
CAS# 1279829-64-9

Theoretical Analysis

MedKoo Cat#: 574870

Name: SAR-216471 HCl

CAS#: 1279829-64-9

Chemical Formula: C28H32Cl2N8O3

Exact Mass: 598.1974

Molecular Weight: 599.52

Elemental Analysis: C, 56.10; H, 5.38; Cl, 11.83; N, 18.69; O, 8.01

Price and Availability

Size Price Availability Quantity
10mg USD 425.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
SAR-216471 hydrochloride; SAR-216471 HCl
IUPAC/Chemical Name
5-Chloro-N-[6-[5-methyl-4-(1-oxobutyl)-1H-pyrazol-1-yl]-3-pyridazinyl]-1-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-1H-indole-3-carboxamide hydrochloride
InChi Key
UQLWHBMSQKUYAI-UHFFFAOYSA-N
InChi Code
InChI=1S/C28H31ClN8O3.ClH/c1-4-5-24(38)21-15-30-37(18(21)2)26-9-8-25(32-33-26)31-28(40)22-16-36(23-7-6-19(29)14-20(22)23)17-27(39)35-12-10-34(3)11-13-35;/h6-9,14-16H,4-5,10-13,17H2,1-3H3,(H,31,32,40);1H
SMILES Code
O=C(C1=CN(CC(N2CCN(C)CC2)=O)C3=C1C=C(Cl)C=C3)NC4=NN=C(N5N=CC(C(CCC)=O)=C5C)C=C4.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 599.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Boldron et al (2014) N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist. J.Med.Chem. 57 7293 PMID: 25075638