MedKoo Cat#: 574861 | Name: RN9893 HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

RN-9893 is an antagonist of TRPV4. It is a tri-substituted benzamide compound.

Chemical Structure

RN9893 HCl
RN9893 HCl
CAS#2109450-40-8

Theoretical Analysis

MedKoo Cat#: 574861

Name: RN9893 HCl

CAS#: 2109450-40-8

Chemical Formula: C21H24ClF3N4O5S

Exact Mass: 0.0000

Molecular Weight: 536.95

Elemental Analysis: C, 46.97; H, 4.51; Cl, 6.60; F, 10.61; N, 10.43; O, 14.90; S, 5.97

Price and Availability

Size Price Availability Quantity
10mg USD 500.00 2 Weeks
50mg USD 1,500.00 2 Weeks
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Synonym
RN-9893 hydrochloride; RN-9893 HCl, RN9893 HCl, RN 9893 HCl; RN9893 hydrochloride; RN 9893 hydrochloride;
IUPAC/Chemical Name
N-[4-[[4-(1-Methylethyl)-1-piperazinyl]sulfonyl]phenyl]-2-nitro-4-(trifluoromethyl)benzamide Hydrochloride
InChi Key
ULUOUAGDTULBRZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H23F3N4O5S.ClH/c1-14(2)26-9-11-27(12-10-26)34(32,33)17-6-4-16(5-7-17)25-20(29)18-8-3-15(21(22,23)24)13-19(18)28(30)31;/h3-8,13-14H,9-12H2,1-2H3,(H,25,29);1H
SMILES Code
O=C(NC1=CC=C(S(=O)(N2CCN(C(C)C)CC2)=O)C=C1)C3=CC=C(C(F)(F)F)C=C3[N+]([O-])=O.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data

Preparing Stock Solutions

The following data is based on the product molecular weight 536.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Wei ZL, Nguyen MT, O'Mahony DJ, Acevedo A, Zipfel S, Zhang Q, Liu L, Dourado M, Chi C, Yip V, DeFalco J, Gustafson A, Emerling DE, Kelly MG, Kincaid J, Vincent F, Duncton MA. Identification of orally-bioavailable antagonists of the TRPV4 ion-channel. Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5. doi: 10.1016/j.bmcl.2015.06.098. Epub 2015 Jul 6. PMID: 26235950.