MedKoo Cat#: 463049 | Name: Gastrofenzin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Gastrofenzin is an antiulcer drug. It has also been shown to exhibit gonadotropic effects.

Chemical Structure

Gastrofenzin
Gastrofenzin
CAS#89845-17-0

Theoretical Analysis

MedKoo Cat#: 463049

Name: Gastrofenzin

CAS#: 89845-17-0

Chemical Formula: C19H22Cl2N2O2

Exact Mass: 380.1058

Molecular Weight: 381.30

Elemental Analysis: C, 59.85; H, 5.82; Cl, 18.59; N, 7.35; O, 8.39

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Gastrofenzin; Gastrophenzine; Gastrophensin;
IUPAC/Chemical Name
ethyl (4-(4-chlorophenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-8-yl)carbamate hydrochloride
InChi Key
MYXXVPPYQMJHGO-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H21ClN2O2.ClH/c1-3-24-19(23)21-18-6-4-5-15-16(11-22(2)12-17(15)18)13-7-9-14(20)10-8-13;/h4-10,16H,3,11-12H2,1-2H3,(H,21,23);1H
SMILES Code
CCOC(Nc1c2c(C(c3ccc(Cl)cc3)CN(C2)C)ccc1)=O.Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 381.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Antov G, Zaĭkov Kh, Mikhaĭlova A, Khalkova Zh, Popov T, Tasheva M, Mitova S, Dinoeva S, Kapurgov V. Toksikologichna kharakteristika na "Gastrofenzin". III. Khronichna oralna toksichnost [The toxicological characteristics of Gastrofenzin. III. Its chronic oral toxicity]. Probl Khig. 1996;21:96-102. Bulgarian. PMID: 9190605. 2: Mikhaĭlova A, Antov G, Khalkova Zh, Zaĭkov Kh, Tasheva M, Dinoeva S. Toksikologichna kharakteristika na "Gastrofenzin". II. Podostra oralna toksichnost [The toxicological characteristics of Gastrofenzin. II. Its subacute oral toxicity]. Probl Khig. 1996;21:88-96. Bulgarian. PMID: 9190604. 3: Khalkova Zh, Zaĭkov Kh, Antov G, Mikhaĭlova A, Ivanova N. Toksikologichna kharakteristika na "Gastrofenzin". I. Ostra toksichnost (oralna, podkozhna, intravenozna) [The toxicological characteristics of Gastrofenzin. I. Its acute toxicity (oral, subcutaneous and intravenous)]. Probl Khig. 1996;21:81-8. Bulgarian. PMID: 9190603. 4: Ilieva P, Ivanova-Chemishanska L, Antov G. Toksikologichna kharakteristika na "Gastrofenzin". IV. Gonadotropno deĭstvie [The toxicological characteristics of Gastrofenzin. IV. Its gonadotropic action]. Probl Khig. 1996;21:102-6. Bulgarian. PMID: 9190585. 5: Mirkova E. Genotoksichnost i kantserogenen potentsial na gastrofenzin [The genotoxicity and carcinogenic potential of gastrofenzin]. Eksp Med Morfol. 1994;32(3-4):57-68. Bulgarian. PMID: 8857033. 6: Ivanova N, Mondeshka D, Ivanov C, Angelova I, Terziyska S, Paskov V. A new class of antiulcer drugs. I. Antiulcer effect of AN5, a 4-phenyl- tetrahydroisoquinoline derivative, on different experimental models of ulcer in rats. Methods Find Exp Clin Pharmacol. 1990 Jul-Aug;12(6):401-10. PMID: 2087139.