MedKoo Cat#: 574840 | Name: Paroxol
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Paroxol is an intermediate in the synthesis of Paroxetine -- a selective serotonin reuptake inhibitor.

Chemical Structure

Paroxol
Paroxol
CAS#105812-81-5

Theoretical Analysis

MedKoo Cat#: 574840

Name: Paroxol

CAS#: 105812-81-5

Chemical Formula: C13H18FNO

Exact Mass: 223.1372

Molecular Weight: 223.29

Elemental Analysis: C, 69.93; H, 8.13; F, 8.51; N, 6.27; O, 7.17

Price and Availability

Size Price Availability Quantity
1g USD 200.00 2 Weeks
5g USD 305.00 2 Weeks
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Related CAS #
No Data
Synonym
Paroxol
IUPAC/Chemical Name
(4R,3S)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol
InChi Key
CXRHUYYZISIIMT-AAEUAGOBSA-N
InChi Code
InChI=1S/C13H18FNO/c1-15-7-6-13(11(8-15)9-16)10-2-4-12(14)5-3-10/h2-5,11,13,16H,6-9H2,1H3/t11-,13-/m0/s1
SMILES Code
OC[C@@H]1CN(C)CC[C@H]1C2=CC=C(F)C=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 223.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Bao Z, Su B, Xing H, Yang Y, Ren Q. Enantioseparation of racemic paroxol on an amylose-based chiral stationary phase by supercritical fluid chromatography. J Sep Sci. 2010 Oct;33(20):3256-62. doi: 10.1002/jssc.201000422. PMID: 20836081.