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MedKoo Cat#: 463034 | Name: Adenosine phosphosulfate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Adenosine phosphosulfate is involved in sulfate/sulfite metabolism in humans.

Chemical Structure

Adenosine phosphosulfate
CAS#485-84-7

Theoretical Analysis

MedKoo Cat#: 463034

Name: Adenosine phosphosulfate

CAS#: 485-84-7

Chemical Formula: C10H14N5O10PS

Exact Mass: 427.0199

Molecular Weight: 427.28

Elemental Analysis: C, 28.11; H, 3.30; N, 16.39; O, 37.44; P, 7.25; S, 7.50

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Adenosine 5'-phosphosulfate; Adenosine-5'-phosphosulfate; Adenosine 5'-sulfatophosphate; Adenosine-5'-sulfatophosphate; APS; AMPS; Adenylyl sulfate; 5'-Adenylyl sulfate;
IUPAC/Chemical Name
(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphoric) sulfuric anhydride
InChi Key
IRLPACMLTUPBCL-KQYNXXCUSA-N
InChi Code
InChI=1S/C10H14N5O10PS/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-26(18,19)25-27(20,21)22/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H2,11,12,13)(H,20,21,22)/t4-,6-,7-,10-/m1/s1
SMILES Code
Nc1c2ncn([C@@H]3O[C@@H]([C@H]([C@H]3O)O)COP(O)(OS(=O)(O)=O)=O)c2ncn1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 427.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PMID: 32560561; PMCID: PMC7357011. 7: Cohen A, Hacham Y, Welfe Y, Khatib S, Avice JC, Amir R. Evidence of a significant role of glutathione reductase in the sulfur assimilation pathway. Plant J. 2020 Apr;102(2):246-261. doi: 10.1111/tpj.14621. Epub 2020 Jan 11. PMID: 31782847. 8: Siddiqui MH, Alamri S, Alsubaie QD, Ali HM, Khan MN, Al-Ghamdi A, Ibrahim AA, Alsadon A. Exogenous nitric oxide alleviates sulfur deficiency-induced oxidative damage in tomato seedlings. Nitric Oxide. 2020 Jan 1;94:95-107. doi: 10.1016/j.niox.2019.11.002. Epub 2019 Nov 7. PMID: 31707015. 9: Xu Z, Wang M, Xu D, Xia Z. The Arabidopsis APR2 positively regulates cadmium tolerance through glutathione-dependent pathway. Ecotoxicol Environ Saf. 2020 Jan 15;187:109819. doi: 10.1016/j.ecoenv.2019.109819. Epub 2019 Oct 22. PMID: 31654864. 10: Oshiki M, Fukushima T, Kawano S, Kasahara Y, Nakagawa J. Thiocyanate Degradation by a Highly Enriched Culture of the Neutrophilic Halophile Thiohalobacter sp. Strain FOKN1 from Activated Sludge and Genomic Insights into Thiocyanate Metabolism. Microbes Environ. 2019 Dec 27;34(4):402-412. doi: 10.1264/jsme2.ME19068. Epub 2019 Oct 19. PMID: 31631078; PMCID: PMC6934394. 11: Chen FF, Chien CY, Cho CC, Chang YY, Hsu CH. C-terminal Redox Domain of Arabidopsis APR1 is a Non-Canonical Thioredoxin Domain with Glutaredoxin Function. Antioxidants (Basel). 2019 Oct 8;8(10):461. doi: 10.3390/antiox8100461. PMID: 31597378; PMCID: PMC6827007. 12: Eltan M, Yavas Abali Z, Arslan Ates E, Kirkgoz T, Kaygusuz SB, Türkyılmaz A, Bereket A, Turan S, Guran T. Low DHEAS Concentration in a Girl Presenting with Short Stature and Premature Pubarche: A Novel PAPSS2 Gene Mutation. Horm Res Paediatr. 2019;92(4):262-268. doi: 10.1159/000502114. Epub 2019 Aug 28. PMID: 31461705. 13: Mi-Ichi F, Ishikawa T, Tam VK, Deloer S, Hamano S, Hamada T, Yoshida H. Characterization of Entamoeba histolytica adenosine 5'-phosphosulfate (APS) kinase; validation as a target and provision of leads for the development of new drugs against amoebiasis. PLoS Negl Trop Dis. 2019 Aug 19;13(8):e0007633. doi: 10.1371/journal.pntd.0007633. PMID: 31425516; PMCID: PMC6715247. 14: Wójcik-Augustyn A, Johansson AJ, Borowski T. Mechanism of Sulfate Activation Catalyzed by ATP Sulfurylase - Magnesium Inhibits the Activity. Comput Struct Biotechnol J. 2019 Jun 18;17:770-784. doi: 10.1016/j.csbj.2019.06.016. PMID: 31312415; PMCID: PMC6607087. 15: Günal S, Hardman R, Kopriva S, Mueller JW. Sulfation pathways from red to green. J Biol Chem. 2019 Aug 16;294(33):12293-12312. doi: 10.1074/jbc.REV119.007422. Epub 2019 Jul 2. PMID: 31270211; PMCID: PMC6699852. 16: Santos HJ, Hanadate Y, Imai K, Nozaki T. An Entamoeba-Specific Mitosomal Membrane Protein with Potential Association to the Golgi Apparatus. Genes (Basel). 2019 May 13;10(5):367. doi: 10.3390/genes10050367. 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