MedKoo Cat#: 574822 | Name: NSC-13755
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NSC-13755 is a human flap endonuclease 1 (FEN1) inhibitor.

Chemical Structure

NSC-13755
NSC-13755
CAS#5430-24-0

Theoretical Analysis

MedKoo Cat#: 574822

Name: NSC-13755

CAS#: 5430-24-0

Chemical Formula: C7H6NO7Sb

Exact Mass: 336.9182

Molecular Weight: 337.89

Elemental Analysis: C, 24.88; H, 1.79; N, 4.15; O, 33.15; Sb, 36.04

Price and Availability

Size Price Availability Quantity
5mg USD 270.00 2 Weeks
10mg USD 445.00 2 Weeks
25mg USD 775.00 2 Weeks
50mg USD 1,150.00 2 Weeks
100mg USD 1,745.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
NSC-13755; NSC13755; NSC 13755
IUPAC/Chemical Name
2-nitro-4-stibonobenzoic acid
InChi Key
HUAYIYWLCZXNRE-UHFFFAOYSA-L
InChi Code
InChI=1S/C7H4NO4.2H2O.O.Sb/c9-7(10)5-3-1-2-4-6(5)8(11)12;;;;/h1,3-4H,(H,9,10);2*1H2;;/q;;;;+2/p-2
SMILES Code
O=C(O)C1=CC=C([Sb](O)(O)=O)C=C1[N+]([O-])=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
NSC-13755 is a human flap endonuclease 1 (FEN1) inhibitor.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 337.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1. Hamza A, Driessen MRM, Tammpere E, O'Neil NJ, Hieter P. Cross-Species Complementation of Nonessential Yeast Genes Establishes Platforms for Testing Inhibitors of Human Proteins. Genetics. 2020 Mar;214(3):735-747. doi: 10.1534/genetics.119.302971. Epub 2020 Jan 14. PMID: 31937519; PMCID: PMC7054014. 2. Dorjsuren D, Kim D, Maloney DJ, Wilson DM 3rd, Simeonov A. Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity. Nucleic Acids Res. 2011 Jan;39(2):e11. doi: 10.1093/nar/gkq1082. Epub 2010 Nov 9. PMID: 21062821; PMCID: PMC3025571.