IUPAC/Chemical Name
1-Hexadecanol
InChi Key
BXWNKGSJHAJOGX-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H34O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h17H,2-16H2,1H3
SMILES Code
CCCCCCCCCCCCCCCCO
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
242.45
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Al-Hashimi NN, Shahin RO, Al-Hashimi AN, Al Ajeal AM, Tahtamouni LH, Basheer C. Cetyl-alcohol-reinforced hollow fiber solid/liquid-phase microextraction and HPLC-DAD analysis of ezetimibe and simvastatin in human plasma and urine. Biomed Chromatogr. 2019 Feb;33(2):e4410. doi: 10.1002/bmc.4410. Epub 2018 Nov 12. PMID: 30315647.
2: Dastidar DG, Das A, Datta S, Ghosh S, Pal M, Thakur NS, Banerjee UC, Chakrabarti G. Paclitaxel-encapsulated core-shell nanoparticle of cetyl alcohol for active targeted delivery through oral route. Nanomedicine (Lond). 2019 Aug;14(16):2121-2150. doi: 10.2217/nnm-2018-0419. Epub 2019 Aug 14. PMID: 31411540.
3: Nawale L, Dubey P, Chaudhari B, Sarkar D, Prabhune A. Anti-proliferative effect of novel primary cetyl alcohol derived sophorolipids against human cervical cancer cells HeLa. PLoS One. 2017 Apr 18;12(4):e0174241. doi: 10.1371/journal.pone.0174241. PMID: 28419101; PMCID: PMC5395175.
4: Knijp J, Bruynzeel DP, Rustemeyer T. Diagnosing lanolin contact allergy with lanolin alcohol and Amerchol L101. Contact Dermatitis. 2019 May;80(5):298-303. doi: 10.1111/cod.13210. Epub 2019 Mar 19. PMID: 30624788; PMCID: PMC6593808.
5: Sepulveda E, Kildsig DO, Ghaly ES. Relationship between internal phase volume and emulsion stability: the cetyl alcohol/stearyl alcohol system. Pharm Dev Technol. 2003 Aug;8(3):263-75. doi: 10.1081/pdt-120022155. PMID: 12901692.
6: Nguyen SH, Dang TP, Maibach HI. Comedogenicity in rabbit: some cosmetic ingredients/vehicles. Cutan Ocul Toxicol. 2007;26(4):287-92. doi: 10.1080/15569520701555383. PMID: 18058303.
7: Draelos ZD, Gunt H, Levy SB. Natural Skin Care Products as Adjunctive to Prescription Therapy in Moderate to Severe Rosacea. J Drugs Dermatol. 2019 Feb 1;18(2):141-146. PMID: 30794364.
8: Bi L, Wehrung D, Oyewumi MO. Contributory roles of innate properties of cetyl alcohol/gelucire nanoparticles to antioxidant and anti-inflammation activities of quercetin. Drug Deliv Transl Res. 2013 Aug;3(4):318-29. doi: 10.1007/s13346-013-0130-6. PMID: 25788280.
9: Komamura H, Doi T, Inui S, Yoshikawa K. A case of contact dermatitis due to impurities of cetyl alcohol. Contact Dermatitis. 1997 Jan;36(1):44-6. doi: 10.1111/j.1600-0536.1997.tb00921.x. PMID: 9034687.
10: Koziara JM, Oh JJ, Akers WS, Ferraris SP, Mumper RJ. Blood compatibility of cetyl alcohol/polysorbate-based nanoparticles. Pharm Res. 2005 Nov;22(11):1821-8. doi: 10.1007/s11095-005-7547-7. Epub 2005 Aug 26. PMID: 16132346.