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MedKoo Cat#: 462991 | Name: Aminochlorambucil

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aminochlorambucil is a biochemical that has shown to have an immunosuppressive effect on adjuvant arthritis in rats.

Chemical Structure

Aminochlorambucil
Aminochlorambucil
CAS#3688-35-5

Theoretical Analysis

MedKoo Cat#: 462991

Name: Aminochlorambucil

CAS#: 3688-35-5

Chemical Formula: C14H20Cl2N2O2

Exact Mass: 318.0902

Molecular Weight: 319.23

Elemental Analysis: C, 52.68; H, 6.32; Cl, 22.21; N, 8.78; O, 10.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
NSC 260461; NSC-260461; NSC260461;
IUPAC/Chemical Name
2-amino-4-(4-(bis(2-chloroethyl)amino)phenyl)butanoic acid
InChi Key
WBIFEHLOTPXXKS-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H20Cl2N2O2/c15-7-9-18(10-8-16)12-4-1-11(2-5-12)3-6-13(17)14(19)20/h1-2,4-5,13H,3,6-10,17H2,(H,19,20)
SMILES Code
NC(C(O)=O)CCc1ccc(N(CCCl)CCCl)cc1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 319.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Redel J, Brouilhet H, Bazely N, Marchal S, Rabaud M, Delbarre F. Réactivité chimique et propriétés biologiques dans la série de l'aminochlorambucil [Chemical reactivity and biological properties of a series of aminochlorambucil derivatives]. C R Acad Hebd Seances Acad Sci D. 1978 Mar 20;286(11):905-7. French. PMID: 96958. 2: Dunn CD, Elson LA. The comparative effect of busulphan ('Myleran') and aminochlorambucil on haemopoietic colony forming units in the rat. Cell Tissue Kinet. 1970 Apr;3(2):131-41. doi: 10.1111/j.1365-2184.1970.tb00260.x. PMID: 4942743. 3: CREE IC, HALLENBECK GA, SHORTER RG. INEFFECTIVENESS OF AMINOCHLORAMBUCIL IN DELAYING REJECTION OF CANINE RENAL HOMOGRAFTS. Transplantation. 1965 May;3:451-2. doi: 10.1097/00007890-196505000-00015. PMID: 14285097. 4: FLOERSHEIM GL, ELSON LA. [Restoration of hematopoiesis following a lethal dose of dimethyl myleran by isologic bone marrow transplantation in mice. Experiments on modification of intolerance to homologous bone marrow by 6-mercaptopurine, aminochlorambucil and cortisone]. Acta Haematol. 1961;26:233-45. German. doi: 10.1159/000206657. PMID: 13893617.