MedKoo Cat#: 462975 | Name: Ginsenoside F3
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ginsenoside F3 is a ginsenoside that has been found in P. ginseng and has immunomodulatory activity. It increases proliferation of isolated mouse spleen cells and the production of IL-2 and IFN-γ, as well as decreases the production of IL-4 and IL-10, when used at concentrations ranging from 0.1 to 100 µM. Ginsenoside F3 also increases the DNA binding activity of NF-κB induced by concanavalin A in isolated mouse spleen cells.

Chemical Structure

Ginsenoside F3
Ginsenoside F3
CAS#62025-50-7

Theoretical Analysis

MedKoo Cat#: 462975

Name: Ginsenoside F3

CAS#: 62025-50-7

Chemical Formula: C41H70O13

Exact Mass: 770.4816

Molecular Weight: 771.00

Elemental Analysis: C, 63.87; H, 9.15; O, 26.98

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 650.00 2 Weeks
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Related CAS #
No Data
Synonym
Ginsenoside F3; Ginsenoside-F3
IUPAC/Chemical Name
(2S,3R,4S,5S,6R)-2-(((S)-6-methyl-2-((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,6,12-trihydroxy-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)hept-5-en-2-yl)oxy)-6-((((2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3,4,5-triol
InChi Key
HJRVLGWTJSLQIG-ABNMXWHVSA-N
InChi Code
InChI=1S/C41H70O13/c1-20(2)10-9-13-41(8,54-36-33(50)31(48)30(47)25(53-36)19-52-35-32(49)29(46)24(44)18-51-35)21-11-15-39(6)28(21)22(42)16-26-38(5)14-12-27(45)37(3,4)34(38)23(43)17-40(26,39)7/h10,21-36,42-50H,9,11-19H2,1-8H3/t21-,22+,23-,24-,25+,26+,27-,28-,29-,30+,31-,32+,33+,34-,35-,36-,38+,39+,40+,41-/m0/s1
SMILES Code
C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O)C)(C[C@H](O)[C@@]2([H])C3(C)C)[C@]4([C@@]1([H])[C@]([C@@](CC/C=C(C)/C)(C)O[C@@H]([C@@H]([C@@H](O)[C@@H]5O)O)O[C@@H]5CO[C@H](OC[C@H](O)[C@@H]6O)[C@@H]6O)([H])CC4)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 771.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Du Z, Li J, Zhang X, Pei J, Huang L. An Integrated LC-MS-Based Strategy for the Quality Assessment and Discrimination of Three Panax Species. Molecules. 2018 Nov 15;23(11):2988. doi: 10.3390/molecules23112988. PMID: 30445785; PMCID: PMC6278395. 2: Li KK, Xu F, Gong XJ. Isolation, Purification and Quantification of Ginsenoside F₅ and F₃ Isomeric Compounds from Crude Extracts of Flower Buds of Panax ginseng. Molecules. 2016 Mar 9;21(3):315. doi: 10.3390/molecules21030315. PMID: 27005606; PMCID: PMC6273083. 3: Yoshizaki K, Devkota HP, Yahara S. Four new triterpenoid saponins from the leaves of Panax japonicus grown in southern Miyazaki Prefecture (4). Chem Pharm Bull (Tokyo). 2013;61(3):273-8. doi: 10.1248/cpb.c12-00794. Epub 2012 Dec 14. PMID: 23238233. 4: Yoshizaki K, Yahara S. New triterpenoid saponins from leaves of Panax japonicus (3). Saponins of the specimens collected in Miyazaki prefecture. Nat Prod Commun. 2012 Apr;7(4):491-3. PMID: 22574450. 5: Yu JL, Dou DQ, Chen XH, Yang HZ, Guo N, Cheng GF. Immunoenhancing activity of protopanaxatriol-type ginsenoside-F3 in murine spleen cells. Acta Pharmacol Sin. 2004 Dec;25(12):1671-6. PMID: 15569414. 6: Zhang YW, Dou DQ, Zhang L, Chen YJ, Yao XS. Effects of ginsenosides from Panax ginseng on cell-to-cell communication function mediated by gap junctions. Planta Med. 2001 Jul;67(5):417-22. doi: 10.1055/s-2001-15816. PMID: 11488454. 7: Dou D, Wen Y, Weng M, Pei Y, Chen Y. [Minor saponins from leaves of Panax ginseng C.A. Meyer]. Zhongguo Zhong Yao Za Zhi. 1997 Jan;22(1):35-7, 62. Chinese. PMID: 10683909.