GLPG2451 is a cystic fibrosis transmembrane conductance regulator potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM.
MedKoo Cat#: 462962
Name: GLPG2451
CAS#: 2055015-61-5
Chemical Formula: C16H16F3N3O5S
Exact Mass: 419.0763
Molecular Weight: 419.38
Elemental Analysis: C, 45.82; H, 3.85; F, 13.59; N, 10.02; O, 19.07; S, 7.64
The following data is based on the product molecular weight 419.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
