MedKoo Cat#: 462938 | Name: Amidosulfuron
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Amidosulfuron is a broad spectrum herbicide that has approval for use in the EU. It is volatile, highly soluble in water and has a high potential for leaching to groundwater. It is not persistent in soil systems but may be persistent in water under certain conditions. Amidosulfuron has a low mammalian toxicity and would not be expected to bioaccumulate. It is moderately toxic to most terrestrial and aquatic species.

Chemical Structure

Amidosulfuron
Amidosulfuron
CAS#120923-37-7

Theoretical Analysis

MedKoo Cat#: 462938

Name: Amidosulfuron

CAS#: 120923-37-7

Chemical Formula: C9H15N5O7S2

Exact Mass: 369.0413

Molecular Weight: 369.37

Elemental Analysis: C, 29.27; H, 4.09; N, 18.96; O, 30.32; S, 17.36

Price and Availability

Size Price Availability Quantity
25mg USD 350.00 2 Weeks
100mg USD 650.00 2 Weeks
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Related CAS #
No Data
Synonym
UNII-6ZNU868K0S;
IUPAC/Chemical Name
N-(N-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)sulfamoyl)-N-methylmethanesulfonamide
InChi Key
CTTHWASMBLQOFR-UHFFFAOYSA-N
InChi Code
InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)
SMILES Code
COc1nc(NC(NS(=O)(N(S(=O)(C)=O)C)=O)=O)nc(OC)c1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 369.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Liu XQ, Yu CY, Dong JG, Hu SW, Xu AX. Acetolactate Synthase-Inhibiting Gametocide Amidosulfuron Causes Chloroplast Destruction, Tissue Autophagy, and Elevation of Ethylene Release in Rapeseed. Front Plant Sci. 2017 Sep 21;8:1625. doi: 10.3389/fpls.2017.01625. PMID: 28983304; PMCID: PMC5613135. 2: Benzi M, Robotti E, Gianotti V. Study on the photodegradation of amidosulfuron in aqueous solutions by LC-MS/MS. Environ Sci Pollut Res Int. 2013 Dec;20(12):9034-43. doi: 10.1007/s11356-013-1900-x. Epub 2013 Jun 16. PMID: 23771442. 3: Cheng Y, Lonhienne T, Garcia MD, Williams CM, Schenk G, Guddat LW. Crystal Structure of the Commercial Herbicide, Amidosulfuron, in Complex with Arabidopsis thaliana Acetohydroxyacid Synthase. J Agric Food Chem. 2023 Apr 5;71(13):5117-5126. doi: 10.1021/acs.jafc.2c08528. Epub 2023 Mar 21. PMID: 36943718. 4: Polati S, Bottaro M, Frascarolo P, Gosetti F, Gianotti V, Gennaro MC. HPLC-UV and HPLC-MSn multiresidue determination of amidosulfuron, azimsulfuron, nicosulfuron, rimsulfuron, thifensulfuron methyl, tribenuron methyl and azoxystrobin in surface waters. Anal Chim Acta. 2006 Oct 10;579(2):146-51. doi: 10.1016/j.aca.2006.07.034. Epub 2006 Jul 22. PMID: 17723738. 5: Kos K, Celar FA. Sensitivity of the entomopathogenic fungus Beauveria bassiana (Bals.-Criv.) Vuill. to selected herbicides. Pest Manag Sci. 2013 Jun;69(6):717-21. doi: 10.1002/ps.3427. Epub 2012 Nov 9. PMID: 23139237. 6: Vítek P, Novotná K, Hodaňová P, Rapantová B, Klem K. Detection of herbicide effects on pigment composition and PSII photochemistry in Helianthus annuus by Raman spectroscopy and chlorophyll a fluorescence. Spectrochim Acta A Mol Biomol Spectrosc. 2017 Jan 5;170:234-41. doi: 10.1016/j.saa.2016.07.025. Epub 2016 Jul 15. PMID: 27450121. 7: Harir M, Chnirheb A, Kanawati B, El Azzouzi M, Schmitt-Kopplin P. Chromatography and high-resolution mass spectrometry for the characterization of the degradation products of the photodegradation of amidosulfuron: an analytical approach. J Agric Food Chem. 2013 Jun 5;61(22):5271-8. doi: 10.1021/jf400133w. Epub 2013 May 22. PMID: 23577633. 8: Zhou Y, Zhao M, Meng Z, Wang Z, Men X, Li J, Li H, Yang J. A magnetic graphene-like MoS2 nanocomposite for simultaneous preconcentration of multi-residue herbicides prior to UHPLC with ion trap mass spectrometric detection. Mikrochim Acta. 2019 Jul 2;186(8):486. doi: 10.1007/s00604-019-3536-0. PMID: 31267303. 9: Rejczak T, Tuzimski T. Simple, cost-effective and sensitive liquid chromatography diode array detector method for simultaneous determination of eight sulfonylurea herbicides in soya milk samples. J Chromatogr A. 2016 Nov 18;1473:56-65. doi: 10.1016/j.chroma.2016.10.023. Epub 2016 Oct 12. PMID: 28314393. 10: Blasco C, Picó Y, Andreu V. Analytical method for simultaneous determination of pesticide and veterinary drug residues in milk by CE-MS. Electrophoresis. 2009 May;30(10):1698-707. doi: 10.1002/elps.200800696. PMID: 19384986. 11: Berger BM, Wolfe NL. Multiresidue determination of sulfonylurea herbicides by capillary electrophoresis for hydrolysis studies in water and sediments. Anal Bioanal Chem. 1996 Dec;356(8):508-11. doi: 10.1007/s0021663560508. PMID: 15045218. 12: Osuna MD, Fischer AJ, De Prado R. Herbicide resistance in Aster squamatus conferred by a less sensitive form of acetolactate synthase. Pest Manag Sci. 2003 Nov;59(11):1210-6. doi: 10.1002/ps.757. PMID: 14620047. 13: Gosetti F, Robotti E, Bolfi B, Mazzucco E, Quasso F, Manfredi M, Silvestri S, Facchi A, Marengo E. Monitoring of water quality inflow and outflow of a farm in Italian Padana plain for rice cultivation: a case study of two years. Environ Sci Pollut Res Int. 2019 Jul;26(21):21274-21294. doi: 10.1007/s11356-019-05155-5. Epub 2019 May 23. PMID: 31124062. 14: Pirard C, Widart J, Nguyen BK, Deleuze C, Heudt L, Haubruge E, De Pauw E, Focant JF. Development and validation of a multi-residue method for pesticide determination in honey using on-column liquid-liquid extraction and liquid chromatography-tandem mass spectrometry. J Chromatogr A. 2007 Jun 8;1152(1-2):116-23. doi: 10.1016/j.chroma.2007.03.035. Epub 2007 Mar 16. PMID: 17416380. 15: Skrobek A, Boss D, Défago G, Butt TM, Maurhofer M. Evaluation of different biological test systems to assess the toxicity of metabolites from fungal biocontrol agents. Toxicol Lett. 2006 Feb 8;161(1):43-52. doi: 10.1016/j.toxlet.2005.07.014. Epub 2005 Sep 1. PMID: 16139968.