MedKoo Cat#: 462889 | Name: Ambinine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ambinine is the major alkaloid of the tuber of Corydalis ambigua var. amurensis. It has protective effects on H9C2 myocardial cells.

Chemical Structure

Ambinine
Ambinine
CAS#96935-26-1

Theoretical Analysis

MedKoo Cat#: 462889

Name: Ambinine

CAS#: 96935-26-1

Chemical Formula: C23H27NO6

Exact Mass: 413.1838

Molecular Weight: 413.47

Elemental Analysis: C, 66.81; H, 6.58; N, 3.39; O, 23.22

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Ambinine;
IUPAC/Chemical Name
4,9,10-trimethoxy-5b,12-dimethyl-5b,6,7,11b,12,13-hexahydrobenzo[c][1,3]dioxolo[4,5-i]phenanthridin-6-ol
InChi Key
CUVAOVCIXOPMNR-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H27NO6/c1-23-15-9-18(28-5)21-20(29-11-30-21)14(15)10-24(2)22(23)13-8-17(27-4)16(26-3)6-12(13)7-19(23)25/h6,8-9,19,22,25H,7,10-11H2,1-5H3
SMILES Code
COc1c(OC)cc2c(CC(C3(C2N(Cc4c3cc(OC)c5c4OCO5)C)C)O)c1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 413.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chang S, Yang Z, Han N, Liu Z, Yin J. The antithrombotic, anticoagulant activity and toxicity research of ambinine, an alkaloid from the tuber of Corydalis ambigua var. amurensis. Regul Toxicol Pharmacol. 2018 Jun;95:175-181. doi: 10.1016/j.yrtph.2018.03.004. Epub 2018 Mar 7. PMID: 29524465. 2: Liu Z, Chang S, Guan X, Han N, Yin J. The metabolites of Ambinine, a benzo[c]phenanthridine alkaloid, in rats identified by ultra-performance liquid chromatography-quadrupoletime-of-flight mass spectrometry (UPLC/Q-TOF-MS/MS). J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 15;1033-1034:226-233. doi: 10.1016/j.jchromb.2016.08.018. Epub 2016 Aug 12. PMID: 27570218. 3: Cui Z, Qi ML, Lin L, Yu DQ. [The structure of ambinine isolated from Corydalis ambigua Cham. et Schltd]. Yao Xue Xue Bao. 1984 Dec;19(12):904-8. Chinese. PMID: 6549570.