U 56324 | CAS#75587-96-1

MedKoo Cat#: 462873 | Name: U 56324

Description:

WARNING: This product is for research use only, not for human or veterinary use.

U-56324 is a hypoglycemic agent derived from nicotinic acid. It was found to inhibit the activity of ATP-sensitive potassium channels in excised patches from mouse pancreatic B-cells.

Chemical Structure

U 56324

CAS#75587-96-1

Theoretical Analysis

MedKoo Cat#: 462873

Name: U 56324

CAS#: 75587-96-1

Chemical Formula: C11H15NO3

Exact Mass: 209.1052

Molecular Weight: 209.25

Elemental Analysis: C, 63.14; H, 7.23; N, 6.69; O, 22.94

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

U-56324; Dhnpona;

IUPAC/Chemical Name

6-neopentyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid

InChi Key

FRHCVEBCJCHBAI-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H15NO3/c1-11(2,3)6-7-4-5-8(10(14)15)9(13)12-7/h4-5H,6H2,1-3H3,(H,12,13)(H,14,15)

SMILES Code

CC(C)(CC1=CC=C(C(N1)=O)C(O)=O)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 209.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Hopkins WF, Fatherazi S, Cook DL. The oral hypoglycemic agent, U-56324, inhibits the activity of ATP-sensitive potassium channels in cell-free membrane patches from cultured mouse pancreatic B-cells. FEBS Lett. 1990 Dec 17;277(1-2):101-4. doi: 10.1016/0014-5793(90)80818-4. PMID: 2269336.