6alpha-Fluorotestosterone | CAS#1597-68-8

MedKoo Cat#: 462858 | Name: 6alpha-Fluorotestosterone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

6alpha-Fluorotestosterone is a synthetic nonaromatizable androgen analog of testosterone. It binds to and activates specific nuclear receptors inhibits and is equipotent to testosterone.

Chemical Structure

6alpha-Fluorotestosterone

CAS#1597-68-8

Theoretical Analysis

MedKoo Cat#: 462858

Name: 6alpha-Fluorotestosterone

CAS#: 1597-68-8

Chemical Formula: C19H27FO2

Exact Mass: 306.1995

Molecular Weight: 306.42

Elemental Analysis: C, 74.48; H, 8.88; F, 6.20; O, 10.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Fluorotestosterone; Fluorotestosterone, 6alpha-; U-11207; U 11207; U11207;

IUPAC/Chemical Name

(6S,8R,9S,10R,13S,14S,17S)-6-fluoro-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

InChi Key

GGQPTOITOZXLBE-QXROXWLYSA-N

InChi Code

InChI=1S/C19H27FO2/c1-18-7-5-11(21)9-15(18)16(20)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h9,12-14,16-17,22H,3-8,10H2,1-2H3/t12-,13-,14-,16-,17-,18+,19-/m0/s1

SMILES Code

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)C[C@@H](C4=CC(CC[C@]34C)=O)F

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 306.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kellis JT Jr, Vickery LE. 6 alpha-fluorotestosterone: a nonaromatizable androgen inhibitor of aromatase cytochrome P450. Steroids. 1990 May;55(5):242-6. doi: 10.1016/0039-128x(90)90023-5. PMID: 2360221. 2: Nordeen EJ, Yahr P. Activation and differentiation of sexual behavior and translocation of hypothalamic estrogen receptors in rats by 6 alpha- fluorotestosterone. Horm Behav. 1981 Jun;15(2):123-40. doi: 10.1016/0018-506x(81)90023-4. PMID: 7250906. 3: Choe YS, Katzenellenbogen JA. Synthesis of C-6 fluoroandrogens: evaluation of ligands for tumor receptor imaging. Steroids. 1995 May;60(5):414-22. doi: 10.1016/0039-128x(95)00009-f. PMID: 7570716. 4: Yahr P. Two aromatase inhibitors inhibit the ability of a third to promote mating in male rats. Horm Behav. 2015 Sep;75:41-4. doi: 10.1016/j.yhbeh.2015.07.009. Epub 2015 Jul 29. PMID: 26232614; PMCID: PMC4648640.