Synonym
Guanidinoethyl sulfonate; Taurocyamine; Guanidinoethane sulfonic acid; 2-guanidinoethanesulfonic acid; Guanidinoethane sulfonate; NSC 667063; NSC667063;NSC-667063;
IUPAC/Chemical Name
2-[(aminoiminomethyl)amino]-ethanesulfonic acid
InChi Key
JKLRIMRKZBSSED-UHFFFAOYSA-N
InChi Code
InChI=1S/C3H9N3O3S/c4-3(5)6-1-2-10(7,8)9/h1-2H2,(H4,4,5,6)(H,7,8,9)
SMILES Code
OS(CCNC(N)=N)(=O)=O
Appearance
A crystalline solid
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
167.18
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1. Uda, K., Saishoji, N., Ichinari, S., et al. Origin and properties of cytoplasmic and mitochondrial isoforms of taurocyamine kinase. FEBS Journal 272, 3521-3530 (2005).
2. Ohkuma, S., Tamura, J.i., Kuriyama, K., et al. Characteristics of taurine transport in freshly isolated rat hepatocytes. Japan.J.Pharmacol. 31, 1061-1070 (1981).
3. Sergeeva, O.A., Chepkova, A.N., and Hass, H.L. Guanidinoethyl sulphonate is a glycine receptor antagonist in striatum. British Journal of Pharmacology 137, 855-860 (2002).
4. Tanaka, A., Takahashi, Y., Mizokuchi, M., et al. Plasma, urinary, and erythrocyte concentrations of guanidino compounds in patients with chronic renal failure. Ren Fail. 21(5), 499-514 (1999).
