MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 574695 | Name: Febuxostat 67M-4

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Febuxostat 67M-4 is a derivative compound of Febuxostat 67M-1 which is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and reduces the risk of gout or kidney stone formation.

Chemical Structure

Febuxostat 67M-4
Febuxostat 67M-4
CAS#407582-49-4

Theoretical Analysis

MedKoo Cat#: 574695

Name: Febuxostat 67M-4

CAS#: 407582-49-4

Chemical Formula: C16H14N2O5S

Exact Mass: 346.0623

Molecular Weight: 346.36

Elemental Analysis: C, 55.48; H, 4.07; N, 8.09; O, 23.10; S, 9.26

Price and Availability

Size Price Availability Quantity
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Febuxostat 67M-4; Febuxostat-67M-4; Febuxostat (67M-4)
IUPAC/Chemical Name
2-[4-(2-Carboxypropoxy)-3-cyanophenyl]-4-methyl-5-thiazolecarboxylic Acid
InChi Key
LCBACLAPKJRMIF-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H14N2O5S/c1-8(15(19)20)7-23-12-4-3-10(5-11(12)6-17)14-18-9(2)13(24-14)16(21)22/h3-5,8H,7H2,1-2H3,(H,19,20)(H,21,22)
SMILES Code
O=C(C1=C(C)N=C(C2=CC=C(OCC(C(O)=O)C)C(C#N)=C2)S1)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 346.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Xie H, Wang Z, Deng K, Jiang X, Wang L, Lv G. An HPLC-MS/MS method for simultaneous determination of the active metabolites of febuxostat (67M-1, 67M-2 and 67M-4) in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;970:24-30. doi:10.1016/j.jchromb.2014.08.038 2. Mayer MD, Khosravan R, Vernillet L, Wu JT, Joseph-Ridge N, Mulford DJ. Pharmacokinetics and pharmacodynamics of febuxostat, a new non-purine selective inhibitor of xanthine oxidase in subjects with renal impairment. Am J Ther. 2005;12(1):22-34. doi:10.1097/00045391-200501000-00005