MedKoo Cat#: 462776 | Name: Dioctanoyl Glycol
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dioctanoyl glycol is a diacylglycerol kinase inhibitor. It reduces basal and thrombin-stimulated phosphatidic acid levels in washed isolated human platelets when used at concentrations of 30, 100, and 500 μM. Dietary administration of dioctanoyl glycol inhibits the growth of S. litura and H. armigera second instar larvae and induces mortality when applied as a spray.

Chemical Structure

Dioctanoyl Glycol
Dioctanoyl Glycol
CAS#627-86-1

Theoretical Analysis

MedKoo Cat#: 462776

Name: Dioctanoyl Glycol

CAS#: 627-86-1

Chemical Formula: C18H34O4

Exact Mass: 314.2457

Molecular Weight: 314.47

Elemental Analysis: C, 68.75; H, 10.90; O, 20.35

Price and Availability

Size Price Availability Quantity
10mg USD 250.00 2 Weeks
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
2-octanoyloxyethyl octanoate; Dioctanoyl ethylene glycol; diC8-Ethylene Glycol; Ethylene Glycol Dioctanoate; 8:0 Ethylene Glycol; dioctanoylglycol; NSC97300; NSC 97300; NSC-97300;
IUPAC/Chemical Name
ethane-1,2-diyl dioctanoate
InChi Key
HTNFLUQQANUSLR-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H34O4/c1-3-5-7-9-11-13-17(19)21-15-16-22-18(20)14-12-10-8-6-4-2/h3-16H2,1-2H3
SMILES Code
O=C(OCCOC(CCCCCCC)=O)CCCCCCC
Appearance
Oily liquid
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Dioctanoylglycol (Ethylene glycol dicaprylate), a diacylglycerol analog, is a diacylglycerol kinase (DGK) inhibitor (Ki of 58 μM).
In vitro activity:
TBD
In vivo activity:
TBD
Solvent mg/mL mM
Solubility
DMF 30.0 95.40
DMSO 30.0 95.40
Ethanol 30.0 95.40
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 314.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD