Buclosamide | CAS#575-74-6

MedKoo Cat#: 535302 | Name: Buclosamide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Buclosamide is a bioactive chemical.

Chemical Structure

Buclosamide

CAS#575-74-6

Theoretical Analysis

MedKoo Cat#: 535302

Name: Buclosamide

CAS#: 575-74-6

Chemical Formula: C11H14ClNO2

Exact Mass: 227.0713

Molecular Weight: 227.69

Elemental Analysis: C, 58.03; H, 6.20; Cl, 15.57; N, 6.15; O, 14.05

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Buclosamide

IUPAC/Chemical Name

N-Butyl-4-chlorosalicylamide

InChi Key

ZGJHIFYEQJEUKA-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H14ClNO2/c1-2-3-6-13-11(15)9-5-4-8(12)7-10(9)14/h4-5,7,14H,2-3,6H2,1H3,(H,13,15)

SMILES Code

OC1=CC(Cl)=CC=C1C(NCCCC)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 227.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Guha DK, Behera FC, Patro SC. Topical therapy with Jadit (buclosamide) in dermatomycoses. Indian J Dermatol. 1974 Apr;19(3):61-3. PMID: 4426634. 2: Panja BK, Haldar B. A clinical trial with a new topical antimycotic agent 4-chloro-2-hydroxybenzoic acid-n-butylmide i.e. buclosamide. Indian J Dermatol. 1970 Jan;15(2):51-3. PMID: 4914369. 3: Burry JN. Persistent light reactions from buclosamide. Arch Dermatol. 1970 Jan;101(1):95-7. PMID: 5416802. 4: Bruze M, Fregert S. Studies on purity and stability of photopatch test substances. Contact Dermatitis. 1983 Jan;9(1):33-9. doi: 10.1111/j.1600-0536.1983.tb04623.x. PMID: 6839737. 5: Ghosh S, Jana CK. Metal-Free Thermal Activation of Molecular Oxygen Enabled Direct α-CH2-Oxygenation of Free Amines. J Org Chem. 2018 Jan 5;83(1):260-266. doi: 10.1021/acs.joc.7b02630. Epub 2017 Dec 13. PMID: 29182340. 6: JUNG EG, SCHWARZ K. PHOTOALLERGISCHES JADIT-EKZEM [PHOTO-ALLERGIC JADIT ECZEMA]. Dermatologica. 1964;129:401-4. German. PMID: 14223805. 7: Gritiyarangsan P. A three-year photopatch study in Thailand. J Dermatol Sci. 1991 Sep;2(5):371-5. doi: 10.1016/0923-1811(91)90031-r. PMID: 1742247. 8: PEISER B, WEYER H. Antimykotische Therapie mit Jadit in Klinik und Sprechstunde [Antimycotic therapy with jadit in clinical & private practice]. Medizinische. 1959 May 30;4(22):1082-4. German. PMID: 13673860.