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MedKoo Cat#: 535300 | Name: HS 37

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HS 37 is a bioactive chemical.

Chemical Structure

HS 37
HS 37
CAS#31755-25-6

Theoretical Analysis

MedKoo Cat#: 535300

Name: HS 37

CAS#: 31755-25-6

Chemical Formula: C17H25ClN2O2

Exact Mass: 324.1605

Molecular Weight: 324.85

Elemental Analysis: C, 62.86; H, 7.76; Cl, 10.91; N, 8.62; O, 9.85

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
HS 37; HS37; HS-37
IUPAC/Chemical Name
Carbanilic acid, 6-chloro-2-methyl-, N-butyl-3-piperidinyl ester
InChi Key
SUGBVZMJIRBHEZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H25ClN2O2/c1-3-4-10-20-11-6-8-14(12-20)22-17(21)19-16-13(2)7-5-9-15(16)18/h5,7,9,14H,3-4,6,8,10-12H2,1-2H3,(H,19,21)
SMILES Code
O=C(OC1CN(CCCC)CCC1)NC2=C(Cl)C=CC=C2C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 324.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Reddy S, Strunk A, Jemec GBE, Garg A. Incidence of Myocardial Infarction and Cerebrovascular Accident in Patients With Hidradenitis Suppurativa. JAMA Dermatol. 2019 Nov 13;156(1):1-7. doi: 10.1001/jamadermatol.2019.3412. Epub ahead of print. PMID: 31721983; PMCID: PMC6865223. 2: Liu M, Degner J, Davis JW, Idler KB, Nader A, Mostafa NM, Waring JF. Identification of HLA-DRB1 association to adalimumab immunogenicity. PLoS One. 2018 Apr 3;13(4):e0195325. doi: 10.1371/journal.pone.0195325. PMID: 29614084; PMCID: PMC5882140. 3: Ganesan S, Summers CM, Pearce SC, Gabler NK, Valentine RJ, Baumgard LH, Rhoads RP, Selsby JT. Short-term heat stress altered metabolism and insulin signaling in skeletal muscle. J Anim Sci. 2018 Feb 15;96(1):154-167. doi: 10.1093/jas/skx083. PMID: 29432553; PMCID: PMC6140929. 4: Ganesan S, Summers CM, Pearce SC, Gabler NK, Valentine RJ, Baumgard LH, Rhoads RP, Selsby JT. Short-term heat stress causes altered intracellular signaling in oxidative skeletal muscle. J Anim Sci. 2017 Jun;95(6):2438-2451. doi: 10.2527/jas.2016.1233. PMID: 28727070. 5: Cruzen SM, Pearce SC, Baumgard LH, Gabler NK, Huff-Lonergan E, Lonergan SM. Proteomic changes to the sarcoplasmic fraction of predominantly red or white muscle following acute heat stress. J Proteomics. 2015 Oct 14;128:141-53. doi: 10.1016/j.jprot.2015.07.032. Epub 2015 Aug 5. PMID: 26254011. 6: Pearce SC, Sanz Fernandez MV, Torrison J, Wilson ME, Baumgard LH, Gabler NK. Dietary organic zinc attenuates heat stress-induced changes in pig intestinal integrity and metabolism. J Anim Sci. 2015 Oct;93(10):4702-13. doi: 10.2527/jas.2015-9018. PMID: 26523563. 7: Cruzen SM, Baumgard LH, Gabler NK, Pearce SC, Lonergan SM. Temporal proteomic response to acute heat stress in the porcine muscle sarcoplasm. J Anim Sci. 2017 Sep;95(9):3961-3971. doi: 10.2527/jas2017.1375. PMID: 28992025. 8: Richards EH, Dani MP, Lu Y, Butt T, Weaver RJ. Effect of stress on heat shock protein levels, immune response and survival to fungal infection of Mamestra brassicae larvae. J Insect Physiol. 2017 Jan;96:53-63. doi: 10.1016/j.jinsphys.2016.10.013. Epub 2016 Oct 24. PMID: 27789295. 9: Dior M, Delagrèverie H, Duboc H, Jouet P, Coffin B, Brot L, Humbert L, Trugnan G, Seksik P, Sokol H, Rainteau D, Sabate JM. Interplay between bile acid metabolism and microbiota in irritable bowel syndrome. Neurogastroenterol Motil. 2016 Sep;28(9):1330-40. doi: 10.1111/nmo.12829. Epub 2016 Apr 5. PMID: 27060367. 10: Nguyen PH, Greene E, Kong BW, Bottje W, Anthony N, Dridi S. Acute Heat Stress Alters the Expression of Orexin System in Quail Muscle. Front Physiol. 2017 Dec 19;8:1079. doi: 10.3389/fphys.2017.01079. PMID: 29311994; PMCID: PMC5742252. 11: Rigotti P, Baldan N, Valente M, Scappin S, Furian L, Cadrobbi R, Marchini F, Ancona E. Evaluation of 84 elderly donors in renal transplantation. Clin Transplant. 2004 Aug;18(4):440-5. doi: 10.1111/j.1399-0012.2004.00186.x. PMID: 15233823. 12: Chang Y, Chen TY, Chen CH, Crain BJ, Toung TJ, Bhardwaj A. Plasma arginine- vasopressin following experimental stroke: effect of osmotherapy. J Appl Physiol (1985). 2006 May;100(5):1445-51. doi: 10.1152/japplphysiol.00763.2005. Epub 2005 Dec 8. PMID: 16339345. 13: Baum VC, Yemen TA, Baum LD. Immediate 8% sevoflurane induction in children: a comparison with incremental sevoflurane and incremental halothane. Anesth Analg. 1997 Aug;85(2):313-6. doi: 10.1097/00000539-199708000-00013. PMID: 9249106. 14: Kawanishi H, Fujioka H. Heat shock cellular stress on aged gut-associated lymphocytes; mRNA expression of inducible heat shock protein gene and protooncogenes. Dev Comp Immunol. 1994 Mar-Apr;18(2):165-77. doi: 10.1016/0145-305x(94)90244-5. PMID: 8082817. 15: Engberg G, Holmdahl MH, Edström HH. A comparison of the local anesthetic properties of bupivacaine and two new long-acting agents, HS 37 and etidocaine, in epidural analgesia. Acta Anaesthesiol Scand. 1974;18(4):277-89. doi: 10.1111/j.1399-6576.1974.tb01181.x. PMID: 4616601. 16: Koeppel T, Pila O. TEST-RETEST RELIABILITY OF KINEMATIC ASSESSMENTS FOR UPPER LIMB ROBOTIC REHABILITATION. IEEE Trans Neural Syst Rehabil Eng. 2020 Aug 3;PP. doi: 10.1109/TNSRE.2020.3013705. Epub ahead of print. PMID: 32746329. 17: McGlew MJ, Safar P, Stremple P. A simple survival model of volume-controlled hemorrhagic shock in awake rats. Resuscitation. 1991 Apr;21(2-3):247-57. doi: 10.1016/0300-9572(91)90050-9. PMID: 1650026. 18: Popov AV, Kaminskaia AN, Savvateeva-Popova EV. [Courtship behavior, communicative sound production and resistance to stress in Drosophila mutants with defective agnostic gene, coding for LIMK1]. Zh Evol Biokhim Fiziol. 2009 Mar-Apr;45(2):184-90. Russian. PMID: 19435260. 19: Mamon LA, Barabanova LV, Kostromina NN. Chastota neraskhozhdeniia i poter' polovykh khromosom v oogeneze u mutanta I(1) ts 403 Drosophila melanogaster s defektom v sisteme belkov teplovogo shoka pri deĭstvii anoksii i vysokoĭ temperatury [Frequency of non-disjunction and loss of sex chromosomes in oogenesis in the Drosophila melanogaster mutant I(1) ts 403 with a defect in the heat-shock protein system in anoxia and at high temperature]. Genetika. 1992 Apr;28(4):64-71. Russian. PMID: 1639252. 20: Clegg JS, Jackson SA, Van Hoa N, Sorgeloos P. Thermal resistance, developmental rate and heat shock proteins in Artemia franciscana, from San Francisco Bay and southern Vietnam. J Exp Mar Biol Ecol. 2000 Sep 5;252(1):85-96. doi: 10.1016/s0022-0981(00)00239-2. PMID: 10962067.