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MedKoo Cat#: 462665 | Name: Maridomycin IV

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Maridomycin IV is a macrolide antibiotic.

Chemical Structure

Maridomycin IV
Maridomycin IV
CAS#35942-56-4

Theoretical Analysis

MedKoo Cat#: 462665

Name: Maridomycin IV

CAS#: 35942-56-4

Chemical Formula: C40H65NO16

Exact Mass: 815.4303

Molecular Weight: 815.95

Elemental Analysis: C, 58.88; H, 8.03; N, 1.72; O, 31.37

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Maridomycin IV;
IUPAC/Chemical Name
(E)-6-((6-((7-acetoxy-13-hydroxy-8-methoxy-3,12-dimethyl-5-oxo-10-(2-oxoethyl)-4,17-dioxabicyclo[14.1.0]heptadec-14-en-9-yl)oxy)-4-(dimethylamino)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl)oxy)-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl propionate
InChi Key
DOABXUMIXMOBRE-OUKQBFOZSA-N
InChi Code
InChI=1S/C40H65NO16/c1-11-30(45)55-38-23(5)51-32(19-40(38,7)48)56-35-22(4)52-39(34(47)33(35)41(8)9)57-36-25(14-15-42)16-20(2)26(44)12-13-27-28(54-27)17-21(3)50-31(46)18-29(37(36)49-10)53-24(6)43/h12-13,15,20-23,25-29,32-39,44,47-48H,11,14,16-19H2,1-10H3/b13-12+
SMILES Code
CCC(OC1C(OC(OC2C(OC(C(C2N(C)C)O)OC3C(CC(C(/C=C/C4OC4CC(OC(CC(C3OC)OC(C)=O)=O)C)O)C)CC=O)C)CC1(O)C)C)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 815.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nakahama K, Igarasi S. Microbial conversion of antibiotics. IV. Reduction of maridomycin. J Antibiot (Tokyo). 1974 Aug;27(8):605-9. doi: 10.7164/antibiotics.27.605. PMID: 4436146. 2: Harada S, Muroi M, Kondo M, Tsuchiya K, Matsuzawa T. Chemical modification of maridomycin, a new macrolide antibiotic. Antimicrob Agents Chemother. 1973 Aug;4(2):140-8. doi: 10.1128/aac.4.2.140. PMID: 4790934; PMCID: PMC444519. 3: Fujisawa Y, Weisblum B. A family of r-determinants in Streptomyces spp. that specifies inducible resistance to macrolide, lincosamide, and streptogramin type B antibiotics. J Bacteriol. 1981 May;146(2):621-31. doi: 10.1128/JB.146.2.621-631.1981. PMID: 6163765; PMCID: PMC217005. 4: Kondo K. Analytical studies of maridomycin. II. Separation of 9-propionylmaridomycins by thin-layer chromatography. J Chromatogr. 1979 Feb 1;169:337-42. doi: 10.1016/0021-9673(75)85058-8. PMID: 536424.