MedKoo Cat#: 574629 | Name: CID-4785700

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CID-4785700 selectively inhibits both Asf1- and Vps75-bound forms of fungal histone acetyltransferase Rtt109.

Chemical Structure

CID-4785700
CID-4785700
CAS#852935-07-0

Theoretical Analysis

MedKoo Cat#: 574629

Name: CID-4785700

CAS#: 852935-07-0

Chemical Formula: C22H23ClFN3O3

Exact Mass: 431.1412

Molecular Weight: 431.89

Elemental Analysis: C, 61.18; H, 5.37; Cl, 8.21; F, 4.40; N, 9.73; O, 11.11

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Related CAS #
No Data
Synonym
CID-4785700, CID4785700, CID 4785700
IUPAC/Chemical Name
N-[(2-chloro-6-fluorophenyl)methyl]-N-methyl-2,5-dioxo-4-phenyl-4-propyl-1-imidazolidineacetamide
InChi Key
LYOOCPLGHJKLEG-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H23ClFN3O3/c1-3-12-22(15-8-5-4-6-9-15)20(29)27(21(30)25-22)14-19(28)26(2)13-16-17(23)10-7-11-18(16)24/h4-11H,3,12-14H2,1-2H3,(H,25,30)
SMILES Code
O=C(N(CC1=C(F)C=CC=C1Cl)C)CN(C(NC2(C3=CC=CC=C3)CCC)=O)C2=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 431.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Lopes da Rosa J, Bajaj V, Spoonamore J, Kaufman PD. A small molecule inhibitor of fungal histone acetyltransferase Rtt109. Bioorg Med Chem Lett. 2013;23(10):2853-2859. doi:10.1016/j.bmcl.2013.03.112 2. Lopes da Rosa J, Boyartchuk VL, Zhu LJ, Kaufman PD. Histone acetyltransferase Rtt109 is required for Candida albicans pathogenesis. Proc Natl Acad Sci U S A. 2010;107(4):1594-1599. doi:10.1073/pnas.0912427107