MedKoo Cat#: 462546 | Name: DFP00173
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. It is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9.

Chemical Structure

DFP00173
DFP00173
CAS#672286-03-2

Theoretical Analysis

MedKoo Cat#: 462546

Name: DFP00173

CAS#: 672286-03-2

Chemical Formula: C11H7Cl2N3O3S

Exact Mass: 330.9585

Molecular Weight: 332.16

Elemental Analysis: C, 39.78; H, 2.12; Cl, 21.35; N, 12.65; O, 14.45; S, 9.65

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
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Related CAS #
No Data
Synonym
DFP00173; DFP 00173; DFP-00173
IUPAC/Chemical Name
1-(2,6-dichlorophenyl)-3-(5-nitrothiophen-3-yl)urea
InChi Key
AATXXTHMITUAOJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H7Cl2N3O3S/c12-7-2-1-3-8(13)10(7)15-11(17)14-6-4-9(16(18)19)20-5-6/h1-5H,(H2,14,15,17)
SMILES Code
O=C(NC1=CSC([N+]([O-])=O)=C1)NC2=C(Cl)C=CC=C2Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 332.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sonntag Y, Gena P, Maggio A, et al. Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors. J Biol Chem. 2019;294(18):7377-7387. doi:10.1074/jbc.RA118.006083