MedKoo Cat#: 574601 | Name: BM635
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BM635 is an MmpL3 inhibitor with anti-mycobacterial activity.

Chemical Structure

BM635
BM635
CAS#1493762-74-5

Theoretical Analysis

MedKoo Cat#: 574601

Name: BM635

CAS#: 1493762-74-5

Chemical Formula: C25H29FN2O

Exact Mass: 392.2264

Molecular Weight: 392.52

Elemental Analysis: C, 76.50; H, 7.45; F, 4.84; N, 7.14; O, 4.08

Price and Availability

Size Price Availability Quantity
5mg USD 285.00 2 Weeks
10mg USD 450.00 2 Weeks
25mg USD 850.00 2 Weeks
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Related CAS #
No Data
Synonym
BM635, BM 635, BM-635
IUPAC/Chemical Name
4-((1-(4-fluorophenyl)-5-(4-isopropylphenyl)-2-methyl-1H-pyrrol-3-yl)methyl)morpholine
InChi Key
NEEGNYKRJDHJNX-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H29FN2O/c1-18(2)20-4-6-21(7-5-20)25-16-22(17-27-12-14-29-15-13-27)19(3)28(25)24-10-8-23(26)9-11-24/h4-11,16,18H,12-15,17H2,1-3H3
SMILES Code
CC(C1=CC=C(C2=CC(CN3CCOCC3)=C(C)N2C4=CC=C(F)C=C4)C=C1)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 392.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Poce G, Consalvi S, Cocozza M, et al. Pharmaceutical salt of BM635 with improved bioavailability. Eur J Pharm Sci. 2017;99:17-23. doi:10.1016/j.ejps.2016.12.003 2. Poce G, Cocozza M, Alfonso S, et al. In vivo potent BM635 analogue with improved drug-like properties. Eur J Med Chem. 2018;145:539-550. doi:10.1016/j.ejmech.2017.12.075