Zatolmilast is a selective phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory and neuroprotective properties. It has been investigated for treating central nervous system disorders, including Alzheimer's and schizophrenia. By inhibiting PDE4, it increases cyclic AMP levels, modulating inflammatory and cognitive pathways.
MedKoo Cat#: 462518
Name: Zatolmilast
CAS#: 1606974-33-7
Chemical Formula: C21H15ClF3NO2
Exact Mass: 405.0743
Molecular Weight: 405.80
Elemental Analysis: C, 62.16; H, 3.73; Cl, 8.74; F, 14.05; N, 3.45; O, 7.89
The following data is based on the product molecular weight 405.80 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
