MedKoo Cat#: 574589 | Name: Biprofen
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Biprofen is a metabolite of Isopropylbiphenyl -- a COX-2 selective inhibitor -- and an impurity of Flurbiprofen.

Chemical Structure

Biprofen
Biprofen
CAS#6341-72-6

Theoretical Analysis

MedKoo Cat#: 574589

Name: Biprofen

CAS#: 6341-72-6

Chemical Formula: C15H14O2

Exact Mass: 226.0994

Molecular Weight: 226.27

Elemental Analysis: C, 79.62; H, 6.24; O, 14.14

Price and Availability

Size Price Availability Quantity
100mg USD 250.00 2 Weeks
250mg USD 450.00 2 Weeks
1g USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
16300Y1; Biprofen; p-Phenylhydratropic Acid
IUPAC/Chemical Name
2-(4-Biphenylyl)propionic Acid
InChi Key
JALUUBQFLPUJMY-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H14O2/c1-11(15(16)17)12-7-9-14(10-8-12)13-5-3-2-4-6-13/h2-11H,1H3,(H,16,17)
SMILES Code
CC(C1=CC=C(C2=CC=CC=C2)C=C1)C(O)=O
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 226.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: López-Muñoz FJ, Ventura R, Díaz MI, Hernández GP, Domínguez AM, García ML, Cabré F, Mauleón D. Analysis of antinociceptive effects of flurbiprofen enantiomers in a rat model of arthritic pain. Methods Find Exp Clin Pharmacol. 2000 Oct;22(8):641-5. doi: 10.1358/mf.2000.22.8.802277. PMID: 11256237. 2: Perera RW, Lough WJ. Assessment of chiral stationary phases for suitability for combined enantiomeric impurity/related substances assays. J Chromatogr A. 2011 Dec 2;1218(48):8655-63. doi: 10.1016/j.chroma.2011.09.085. Epub 2011 Oct 10. PMID: 22041143. 3: Wright MR, Jamali F. Limited extent of stereochemical conversion of chiral non-steroidal anti-inflammatory drugs induced by derivatization methods employing ethyl chloroformate. J Chromatogr. 1993 Jun 23;616(1):59-65. doi: 10.1016/0378-4347(93)80471-f. PMID: 8376493. 4: Nováková L, Matysová L, Havlíková L, Solich P. Development and validation of HPLC method for determination of indomethacin and its two degradation products in topical gel. J Pharm Biomed Anal. 2005 Apr 29;37(5):899-905. doi: 10.1016/j.jpba.2004.09.012. PMID: 15862664. 5: Smith WL. Flurbiprofen-sepharose chromatography of the prostaglandin synthetase from bovine seminal vesicles. Prostaglandins. 1975 Dec;10(6):983-90. doi: 10.1016/s0090-6980(75)80045-1. PMID: 813277.