NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation.
MedKoo Cat#: 462470
Name: NRX-252262
CAS#: 2438637-61-5
Chemical Formula: C23H17Cl2F3N2O4S
Exact Mass: 544.0238
Molecular Weight: 545.35
Elemental Analysis: C, 50.66; H, 3.14; Cl, 13.00; F, 10.45; N, 5.14; O, 11.73; S, 5.88
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 8.3 | 15.27 |
The following data is based on the product molecular weight 545.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
