CDK4/6-IN-4, the active metabolite of Abemaciclib, is a selective CDK4/6 inhibitor for the treatment of cancer.
MedKoo Cat#: 462469
Name: CDK4/6-IN-4
CAS#: 2138499-06-4
Chemical Formula: C27H32F2N8O
Exact Mass: 522.2667
Molecular Weight: 522.60
Elemental Analysis: C, 62.05; H, 6.17; F, 7.27; N, 21.44; O, 3.06
The following data is based on the product molecular weight 522.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
