MedKoo Cat#: 574543 | Name: AA41612
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

AA41612 is a novel antagonist of melanopsin-mediated phototransduction.

Chemical Structure

AA41612
AA41612
CAS#433690-62-1

Theoretical Analysis

MedKoo Cat#: 574543

Name: AA41612

CAS#: 433690-62-1

Chemical Formula: C12H15Cl2NO3S

Exact Mass: 323.0150

Molecular Weight: 324.22

Elemental Analysis: C, 44.46; H, 4.66; Cl, 21.87; N, 4.32; O, 14.80; S, 9.89

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
200mg USD 1,250.00 2 Weeks
1g USD 4,250.00 2 Weeks
2g USD 6,450.00 2 Weeks
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Related CAS #
No Data
Synonym
AA41612; AA-41612; AA 41612;
IUPAC/Chemical Name
1-(2,5-Dichloro-4-methoxy-benzenesulfonyl)-piperidine
InChi Key
FEMVYIQDVGQFBA-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H15Cl2NO3S/c1-18-11-7-10(14)12(8-9(11)13)19(16,17)15-5-3-2-4-6-15/h7-8H,2-6H2,1H3
SMILES Code
O=S(N1CCCCC1)(C2=CC(Cl)=C(OC)C=C2Cl)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
AA41612 is an antagonist of melanopsin-mediated phototransduction.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 324.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
Jones KA, Hatori M, Mure LS, Bramley JR, Artymyshyn R, Hong SP, Marzabadi M, Zhong H, Sprouse J, Zhu Q, Hartwick AT, Sollars PJ, Pickard GE, Panda S. Small-molecule antagonists of melanopsin-mediated phototransduction. Nat Chem Biol. 2013 Oct;9(10):630-5. doi: 10.1038/nchembio.1333. Epub 2013 Aug 25. PMID: 23974117; PMCID: PMC3839535.