MedKoo Cat#: 462445 | Name: RTC-5
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RTC-5 is an optimized phenothiazine with anti-cancer potency. RTC-5 demonstrates efficacy against a xenograft model of an EGFR driven cancer, its effects is attributed to concomitant negative regulation of PI3K-AKT and RAS-ERK signaling.

Chemical Structure

RTC-5
RTC-5
CAS#1423077-49-9

Theoretical Analysis

MedKoo Cat#: 462445

Name: RTC-5

CAS#: 1423077-49-9

Chemical Formula: C24H22ClF3N2O3S

Exact Mass: 510.0992

Molecular Weight: 510.96

Elemental Analysis: C, 56.42; H, 4.34; Cl, 6.94; F, 11.15; N, 5.48; O, 9.39; S, 6.27

Price and Availability

Size Price Availability Quantity
5mg USD 280.00 2 Weeks
10mg USD 440.00 2 Weeks
25mg USD 800.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
RTC-5; RTC5; RTC 5
IUPAC/Chemical Name
N-(3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)-4-(trifluoromethoxy)benzenesulfonamide
InChi Key
QYOJMNDDVVEPFN-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H22ClF3N2O3S/c25-19-9-8-18-7-6-17-4-1-2-5-22(17)30(23(18)16-19)15-3-14-29-34(31,32)21-12-10-20(11-13-21)33-24(26,27)28/h1-2,4-5,8-13,16,29H,3,6-7,14-15H2
SMILES Code
O=S(C1=CC=C(OC(F)(F)F)C=C1)(NCCCN2C3=CC(Cl)=CC=C3CCC4=CC=CC=C42)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 510.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kastrinsky DB, Sangodkar J, Zaware N, et al. Reengineered tricyclic anti-cancer agents. Bioorg Med Chem. 2015;23(19):6528-6534. doi:10.1016/j.bmc.2015.07.007