AS3334034 | CAS#N/A

MedKoo Cat#: 535108 | Name: AS3334034

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AS3334034 is a Novel Receptor-interacting Protein Kinase 2 (RIP2) Inhibitor.

Chemical Structure

AS3334034

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 535108

Name: AS3334034

CAS#: N/A

Chemical Formula: C18H22N4O3S

Exact Mass: 374.1413

Molecular Weight: 374.46

Elemental Analysis: C, 57.74; H, 5.92; N, 14.96; O, 12.82; S, 8.56

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

AS3334034; AS-3334034; AS 3334034

IUPAC/Chemical Name

7-Methoxy-6-(2-methylpropane-2-sulfonyl)-N-(4-methyl-1H-pyrazol-3-yl)quinolin-4-amine

InChi Key

WCPMUQAUSFXFJE-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H22N4O3S/c1-11-10-20-22-17(11)21-13-6-7-19-14-9-15(25-5)16(8-12(13)14)26(23,24)18(2,3)4/h6-10H,1-5H3,(H2,19,20,21,22)

SMILES Code

CC1=CNN=C1NC2=CC=NC3=CC(OC)=C(S(=O)(C(C)(C)C)=O)C=C23

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 374.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wada Y, Kondo M, Sakairi K, Nagashima A, Tokita K, Tominaga H, Tomiyama H, Ishikawa T. Renoprotective Effects of a Novel Receptor-interacting Protein Kinase 2 Inhibitor, AS3334034, in Uninephrectomized Adriamycin-induced Chronic Kidney Disease Rats. J Pharmacol Exp Ther. 2020 Jun 19:jpet.120.265678. doi: 10.1124/jpet.120.265678. Epub ahead of print. PMID: 32561685.