Synonym
Seco-Rapamycin ethyl ester
IUPAC/Chemical Name
Ethyl (S)-1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,20S,21R)-14,20-dihydroxy-22-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15-tetraen-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate
InChi Key
SIOBWRQYNWVYEE-JZXYALBUSA-N
InChi Code
InChI=1S/C53H85NO14/c1-12-67-52(62)41-20-16-17-25-54(41)51(61)50(60)53(63)38(8)21-23-40(68-53)30-45(64-9)33(3)19-15-13-14-18-32(2)26-36(6)47(58)49(66-11)48(59)37(7)27-34(4)43(56)31-44(57)35(5)28-39-22-24-42(55)46(29-39)65-10/h13-15,18-19,27,32,34-36,38-42,44-46,48-49,55,57,59,63H,12,16-17,20-26,28-31H2,1-11H3/b15-13+,18-14+,33-19+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,42-,44+,45+,46-,48-,49+,53-/m1/s1
SMILES Code
O=C([C@H]1N(C(C([C@@]2(O)[C@H](C)CC[C@@H](C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C([C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(C[C@H](O)[C@H](C)C[C@H]3C[C@@H](OC)[C@H](O)CC3)=O)=O)O2)=O)=O)CCCC1)OCC
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
