IUPAC/Chemical Name
1H-Pyrazole-1-acetamide, N-(3-(diethylamino)propyl)-4,5-diphenyl-
InChi Key
PRHCHMGCDBUACR-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H30N4O/c1-3-27(4-2)17-11-16-25-23(29)19-28-24(21-14-9-6-10-15-21)22(18-26-28)20-12-7-5-8-13-20/h5-10,12-15,18H,3-4,11,16-17,19H2,1-2H3,(H,25,29)
SMILES Code
O=C(NCCCN(CC)CC)CN1N=CC(C2=CC=CC=C2)=C1C3=CC=CC=C3
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
390.53
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Gottlieb SS, Cines M, Pressel MD. The hemodynamic actions of the antiarrhythmic agent ipazilide fumarate in patients with congestive heart failure. Clin Pharmacol Ther. 1994 Jul;56(1):75-81. doi: 10.1038/clpt.1994.103. PMID: 8033497.
2: Greener Y, Mayes BA, Barbolt TA, Kimball JP, Dixon RL, Everett RM, Dean JH, Zelinger DJ, Benziger DP, Ezrin AM. Subchronic oral and intravenous (i.v.) safety evaluation and pharmacokinetics in rats and dogs of ipazilide fumarate (Win 54, 177-4), an antiarrhythmic agent. Fundam Appl Toxicol. 1992 May;18(4):581-9. doi: 10.1016/0272-0590(92)90117-z. PMID: 1526370.
3: Greener Y, Barbolt TA, Zelinger DJ, Gossett KA. Chronic (1-year) safety evaluation of ipazilide fumarate, an antiarrhythmic agent, administered orally to rats. Fundam Appl Toxicol. 1993 Feb;20(2):147-54. doi: 10.1006/faat.1993.1020. PMID: 8449385.
