MedKoo Cat#: 462415 | Name: IZCZ-3
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

IZCZ-3 is a potent c-MYC transcription inhibitor with antitumor activity.

Chemical Structure

IZCZ-3
IZCZ-3
CAS#2223019-53-0

Theoretical Analysis

MedKoo Cat#: 462415

Name: IZCZ-3

CAS#: 2223019-53-0

Chemical Formula: C46H49N7O

Exact Mass: 715.3999

Molecular Weight: 715.95

Elemental Analysis: C, 77.17; H, 6.90; N, 13.70; O, 2.23

Price and Availability

Size Price Availability Quantity
5mg USD 600.00 2 Weeks
10mg USD 1,080.00 2 Weeks
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Related CAS #
No Data
Synonym
IZCZ-3; IZCZ3; IZCZ 3
IUPAC/Chemical Name
9-ethyl-3-(1-(4-methoxyphenyl)-4,5-bis(4-(4-methylpiperazin-1-yl)phenyl)-1H-imidazol-2-yl)-9H-carbazole
InChi Key
SETZGUYDZNTJCI-UHFFFAOYSA-N
InChi Code
InChI=1S/C46H49N7O/c1-5-52-42-9-7-6-8-40(42)41-32-35(14-23-43(41)52)46-47-44(33-10-15-36(16-11-33)50-28-24-48(2)25-29-50)45(53(46)38-19-21-39(54-4)22-20-38)34-12-17-37(18-13-34)51-30-26-49(3)27-31-51/h6-23,32H,5,24-31H2,1-4H3
SMILES Code
COC(C=C1)=CC=C1N2C(C3=CC(C(C=CC=C4)=C4N5CC)=C5C=C3)=NC(C6=CC=C(N7CCN(C)CC7)C=C6)=C2C(C=C8)=CC=C8N9CCN(C)CC9
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 715.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hu MH, Wang YQ, Yu ZY, et al. Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c-MYC Transcription Inhibitor Specifically Targeting the Promoter G-Quadruplex. J Med Chem. 2018;61(6):2447-2459. doi:10.1021/acs.jmedchem.7b01697