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MedKoo Cat#: 535068 | Name: AB-22

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AB-22 is a bioactive chemical.

Chemical Structure

AB-22
AB-22
CAS#1463913-43-0

Theoretical Analysis

MedKoo Cat#: 535068

Name: AB-22

CAS#: 1463913-43-0

Chemical Formula: C22H30ClN7O3

Exact Mass: 475.2099

Molecular Weight: 475.98

Elemental Analysis: C, 55.52; H, 6.35; Cl, 7.45; N, 20.60; O, 10.08

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AB-22; AB 22; AB22
IUPAC/Chemical Name
Hydrazinecarboxamide, N-(2-chloro-6-propoxy-4-pyridinyl)-2-(1,3-dimethyl-4-(1-methylethyl)-1H-pyrazolo(3,4-b)pyridin-6-yl)-2-(2-hydroxyethyl)-
InChi Key
GOQBSVFOBGVWTA-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H30ClN7O3/c1-6-9-33-19-11-15(10-17(23)25-19)24-22(32)28-30(7-8-31)18-12-16(13(2)3)20-14(4)27-29(5)21(20)26-18/h10-13,31H,6-9H2,1-5H3,(H2,24,25,28,32)
SMILES Code
OCCN(C1=CC(C(C)C)=C2C(N(C)N=C2C)=N1)NC(NC3=CC(Cl)=NC(OCCC)=C3)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 475.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: MacLaggan TD, Le CP, Iverson KA, Ellis CL, Allard J, Wilcox-Carrier TJ, Smyth DJ. The clinical impact of a urinary tract infection management bundle in a tertiary-care teaching hospital. Infect Control Hosp Epidemiol. 2019 Jan;40(1):72-78. doi: 10.1017/ice.2018.276. Epub 2018 Dec 3. PMID: 30501661. 2: Choi YM, Kim WG, Kim TY, Bae SJ, Kim HK, Jang EK, Jeon MJ, Han JM, Lee SH, Baek JH, Shong YK, Kim WB. Low levels of serum vitamin D3 are associated with autoimmune thyroid disease in pre-menopausal women. Thyroid. 2014 Apr;24(4):655-61. doi: 10.1089/thy.2013.0460. Epub 2014 Jan 30. PMID: 24320141; PMCID: PMC3993051. 3: Pohlen B, Hawlina M, Šober K, Kopač I. Tooth Shade-Matching Ability Between Groups of Students with Different Color Knowledge. Int J Prosthodont. 2016 Sep- Oct;29(5):487-92. doi: 10.11607/ijp.4712. PMID: 27611754. 4: Mandato VD, Torricelli F, Mastrofilippo V, Ciarlini G, Pirillo D, Annunziata G, Casali B, Abrate M, Sala GB, Aguzzoli L. AB0 Blood Group and Ovarian Cancer Survival. J Cancer. 2019 Apr 25;10(9):1949-1957. doi: 10.7150/jca.29272. PMID: 31205554; PMCID: PMC6548162. 5: Skendros P, Boura P, Kamaria F, Raptopoulou-Gigi M. CD80/CD28 co-stimulation in human brucellosis. Clin Exp Immunol. 2006 Dec;146(3):400-8. doi: 10.1111/j.1365-2249.2006.03223.x. Erratum in: Clin Exp Immunol. 2007 Jan;147(1):197. PMID: 17100758; PMCID: PMC1810400. 6: Velasquez-Munoz A, Manriquez D, Paudyal S, Solano G, Han H, Callan R, Velez J, Pinedo P. Effect of a mechanical grooming brush on the behavior and health of recently weaned heifer calves. BMC Vet Res. 2019 Aug 8;15(1):284. doi: 10.1186/s12917-019-2033-3. PMID: 31395062; PMCID: PMC6686348. 7: Strieder TG, Wenzel BE, Prummel MF, Tijssen JG, Wiersinga WM. Increased prevalence of antibodies to enteropathogenic Yersinia enterocolitica virulence proteins in relatives of patients with autoimmune thyroid disease. Clin Exp Immunol. 2003 May;132(2):278-82. doi: 10.1046/j.1365-2249.2003.02139.x. PMID: 12699417; PMCID: PMC1808711. 8: Maginniss LA, Ekelund SA, Ultsch GR. Blood oxygen transport in common map turtles during simulated hibernation. Physiol Biochem Zool. 2004 Mar- Apr;77(2):232-41. doi: 10.1086/381473. PMID: 15095243. 9: Arck PC, Hertwig K, Hagen E, Hildebrandt M, Klapp BF. Pregnancy as a model of controlled invasion might be attributed to the ratio of CD3/CD8 to CD56. Am J Reprod Immunol. 2000 Jul;44(1):1-8. doi: 10.1111/j.8755-8920.2000.440101.x. PMID: 10976806. 10: Skendros P, Boura P, Chrisagis D, Raptopoulou-Gigi M. Diminished percentage of CD4+ T-lymphocytes expressing interleukine-2 receptor alpha in chronic brucellosis. J Infect. 2007 Feb;54(2):192-7. doi: 10.1016/j.jinf.2006.04.001. Epub 2006 May 23. PMID: 16720045. 11: Baharav E, Gur H, Fishman P, Ziporen L, Blank M, Aelion J, Kotb M, Shoenfeld Y. Superantigens and experimental SLE induced by idiotypic dysregulation. Clin Exp Rheumatol. 1996 Jul-Aug;14(4):359-66. PMID: 8871833. 12: Takeuchi M, Kakiuchi T, Taira S, Nariuchi H. B cells as accessory cells in a Con A response of a T cell clone. Immunobiology. 1987 Dec;176(1-2):1-13. doi: 10.1016/S0171-2985(87)80095-5. PMID: 3129359. 13: Xie J, Joseph KO, Bagby GJ, Giles TD, Greenberg SS. Dissociation of TNF- alpha from endotoxin-induced nitric oxide and acute-phase hypotension. Am J Physiol. 1997 Jul;273(1 Pt 2):H164-74. doi: 10.1152/ajpheart.1997.273.1.H164. PMID: 9249487. 14: Eliasson I. A protein antigen characteristic of Branhamella catarrhalis. Serological identification of the genus. Acta Pathol Microbiol Scand B. 1980 Oct;88(5):281-6. doi: 10.1111/j.1699-0463.1980.tb02642.x. PMID: 6781219.