IUPAC/Chemical Name
Benzamide, 5-chloro-N-(2-(((4-iodophenyl)methyl)methylamino)ethyl)-2-methoxy-4-(methylamino)-
InChi Key
SSXZAENYAVXXOA-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H23ClIN3O2/c1-22-17-11-18(26-3)15(10-16(17)20)19(25)23-8-9-24(2)12-13-4-6-14(21)7-5-13/h4-7,10-11,22H,8-9,12H2,1-3H3,(H,23,25)
SMILES Code
O=C(NCCN(CC1=CC=C(I)C=C1)C)C2=CC(Cl)=C(NC)C=C2OC
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
487.77
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Sánchez-Roa PM, Grigoriadis DE, Wilson AA, Sharkey J, Dannals RF, Villemagne VL, Wong DF, Wagner HN Jr, Kuhar MJ. [125]I-spectramide: a novel benzamide displaying potent and selective effects at the D2 dopamine receptor. Life Sci. 1989;45(19):1821-9. doi: 10.1016/0024-3205(89)90523-7. PMID: 2531826.
2: Wilson AA, Dannals RF, Ravert HT, Wagner HN Jr. Preparation of [11C]- and [125I]IMB: a dopamine D-2 receptor antagonist. Int J Rad Appl Instrum A. 1989;40(5):369-73. doi: 10.1016/0883-2889(89)90199-8. PMID: 2548972.
3: Wong DF, Wilson AA, Chen C, Minkin E, Dannals RF, Ravert HT, Sanchez-Roa P, Villemagne V, Wagner HN Jr. In vivo studies of [125I]iodobenzamide and [11C]iodobenzamide: a ligand suitable for positron emission tomography and single photon emission tomography imaging of cerebral D2 dopamine receptors. Synapse. 1992 Nov;12(3):236-41. doi: 10.1002/syn.890120309. PMID: 1481143.
