MedKoo Cat#: 535060 | Name: Exp 985

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Exp 985 is a radioligand with high specific activity for the angiotensin 1 receptor.

Chemical Structure

Exp 985
Exp 985
CAS#145644-13-9

Theoretical Analysis

MedKoo Cat#: 535060

Name: Exp 985

CAS#: 145644-13-9

Chemical Formula: C29H27ClIN7O2

Exact Mass: 667.0959

Molecular Weight: 667.94

Elemental Analysis: C, 52.15; H, 4.07; Cl, 5.31; I, 19.00; N, 14.68; O, 4.79

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Exp 985; Exp-985; Exp985
IUPAC/Chemical Name
1H-Imidazole-5-carboxamide, 4-chloro-N-(2-(4-hydroxy-3-iodophenyl)ethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-
InChi Key
WMCDNTWPKXBICS-UHFFFAOYSA-N
InChi Code
InChI=1S/C29H27ClIN7O2/c1-2-5-25-33-27(30)26(29(40)32-15-14-18-10-13-24(39)23(31)16-18)38(25)17-19-8-11-20(12-9-19)21-6-3-4-7-22(21)28-34-36-37-35-28/h3-4,6-13,16,39H,2,5,14-15,17H2,1H3,(H,32,40)(H,34,35,36,37)
SMILES Code
O=C(C1=C(Cl)N=C(CCC)N1CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2)NCCC5=CC=C(O)C(I)=C5
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 667.94 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ohyama K, Yamano Y, Sano T, Nakagomi Y, Hamakubo T, Morishima I, Inagami T. Disulfide bridges in extracellular domains of angiotensin II receptor type IA. Regul Pept. 1995 May 30;57(2):141-7. doi: 10.1016/0167-0115(95)00030-f. PMID: 7659790. 2: Chiu AT, McCall DE, Roscoe WA. [125I]EXP985: a highly potent and specific nonpeptide radioligand antagonist for the AT1 angiotensin receptor. Biochem Biophys Res Commun. 1992 Nov 16;188(3):1030-9. doi: 10.1016/0006-291x(92)91335-n. PMID: 1445340.