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MedKoo Cat#: 462350 | Name: MLS000544460

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MLS000544460 is a highly selective and reversible Eya2 phosphatase inhibitor. It inhibits Eya2 phosphatase mediated cell migration and has anti-cancer activity.

Chemical Structure

MLS000544460
CAS#352336-36-8

Theoretical Analysis

MedKoo Cat#: 462350

Name: MLS000544460

CAS#: 352336-36-8

Chemical Formula: 341.0634

Exact Mass: 341.0634

Molecular Weight: 341.36

Elemental Analysis: C, 59.82; H, 3.54; F, 5.57; N, 12.31; O, 9.37; S, 9.39

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
MLS000544460; MLS 000544460; MLS-000544460
IUPAC/Chemical Name
(E)-3-fluoro-N'-((5-(pyridin-2-ylthio)furan-2-yl)methylene)benzohydrazide
InChi Key
VDKNIVFIPSLUFD-RGVLZGJSSA-N
InChi Code
InChI=1S/C17H12FN3O2S/c18-13-5-3-4-12(10-13)17(22)21-20-11-14-7-8-16(23-14)24-15-6-1-2-9-19-15/h1-11H,(H,21,22)/b20-11+
SMILES Code
FC1=CC=CC(C(N/N=C/C2=CC=C(SC3=CC=CC=N3)O2)=O)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 341.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Krueger AB, Drasin DJ, Lea WA, et al. Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration. J Biol Chem. 2014;289(23):16349-16361. doi:10.1074/jbc.M114.566729