DSR-141562, also known as LMN75224 is a phosphodiesterase 1 inhibitors useful for treatment of neurological and psychiatric disorder. DSR-141562 exhibits Efficacies in Animal Models for Positive, Negative, and Cognitive Symptoms Associated with Schizophrenia. DSR-141562 has preferential selectivity for predominantly brain-expressed PDE1B over other PDE1 family members, and high selectivity for the PDE1 family over other PDE families and 65 other tested biologic targets.
MedKoo Cat#: 555816
Name: DSR-141562
CAS#: 2007975-22-4
Chemical Formula: C19H25F3N4O3
Exact Mass: 414.1879
Molecular Weight: 414.43
Elemental Analysis: C, 55.07; H, 6.08; F, 13.75; N, 13.52; O, 11.58
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 25.0 | 60.32 |
The following data is based on the product molecular weight 414.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
