ER-176 is non-radio-labled ligand. [11C]ER176 is a next generation PET radioligand for imaging 18 kDa translocator protein, a biomarker for neuroinflammation. 11C-ER176 displays a higher binding potential and a smaller variability of VT values. Thanks to these characteristics, clinical studies performed with 11C-ER176 are expected to have higher statistical power and thus require fewer subjects.
MedKoo Cat#: 535021
Name: ER-176
CAS#: 1373887-29-6
Chemical Formula: C21H23ClN3O
Exact Mass: 368.1530
Molecular Weight: 368.89
Elemental Analysis: C, 68.38; H, 6.28; Cl, 9.61; N, 11.39; O, 4.34
The following data is based on the product molecular weight 368.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
