MedKoo Cat#: 408108 | Name: GAN91615

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GAN91615, also known as PTP1B-IN-8, is a potent and selective potent protein tyrosine phosphatase-1B (PTP1B) inhibitor extracted from patent CN103626692A, example 1. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

GAN91615
GAN91615
CAS#919091-61-5

Theoretical Analysis

MedKoo Cat#: 408108

Name: GAN91615

CAS#: 919091-61-5

Chemical Formula: C19H13Cl4NO

Exact Mass: 410.9751

Molecular Weight: 413.12

Elemental Analysis: C, 55.24; H, 3.17; Cl, 34.32; N, 3.39; O, 3.87

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Synonym
PTP1B-IN-8; PTP1B-IN 8; PTP1B-IN8; GAN91615; GAN-91615; GAN 91615;
IUPAC/Chemical Name
3,5-bis((E)-3,4-dichlorobenzylidene)piperidin-4-one
InChi Key
GJPXGFGIFQWUOC-ACFHMISVSA-N
InChi Code
InChI=1S/C19H13Cl4NO/c20-15-3-1-11(7-17(15)22)5-13-9-24-10-14(19(13)25)6-12-2-4-16(21)18(23)8-12/h1-8,24H,9-10H2/b13-5+,14-6+
SMILES Code
O=C1/C(CNC/C1=C\C2=CC=C(C(Cl)=C2)Cl)=C/C3=CC=C(C(Cl)=C3)Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
(E,E)-RAMB4 is a potent and selective potent protein tyrosine phosphatase-1B (PTP1B) inhibitor extracted from patent CN103626692A, example 1.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 413.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD